Looking Beneath the Surface in Atopic Dermatitis

This activity is supported by an educational grant from Sanofi Genzyme and Regeneron Pharmaceuticals.

This activity is jointly provided by Global Education Group and Integritas Communications.

Target Audience

The educational design of this activity addresses the needs of dermatologists, allergists, and other clinicians who treat patients with atopic dermatitis.

Statement of Need/Program Overview

Atopic dermatitis is a chronic inflammatory condition that primarily manifests in the skin, although studies continue to elucidate effects in other organ systems throughout the body.¹ An increasing prevalence over the last 2 decades has added to tremendous disease-related burdens faced by patients, family members, and caregivers.^1,2 Current insights into atopic dermatitis pathophysiology and its widespread effects on patient health and quality of life support efforts to accelerate diagnoses and proactive management.^3,4 Moreover, research into the dysregulated cellular and molecular immune processes underlying the pathogenesis and progression of atopic dermatitis has led to new approaches to disease characterization and treatment.^5,6 This Interactive Exchange™ program will open with a brief 3D-animated video focused on the pathophysiologic underpinnings of atopic dermatitis. Expert faculty will then discuss best practices for comprehensive patient evaluations and the clinical profiles of systemic treatment options for patients with moderate-to-severe disease. With an overall goal of improving patient outcomes, this educational session has been designed to allow internationally recognized experts to translate the latest published evidence into actionable recommendations for individualized patient care.

References

1. Nutten S. Atopic dermatitis: global epidemiology and risk factors. Ann Nutr Metab. 2015:66(suppl 1):8-16.
2. Drucker AM, et al. The burden of atopic dermatitis: summary of a report for the National Eczema Association. J Invest Dermatol. 2017;137(1):26-30.
3. Eichenfield LF, et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol. 2014;70(2):338-351.
4. Sidbury R, et al. Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. J Am Acad Dermatol. 2014;71(2): 327-349.
5. Ungar B, et al. An integrated model of atopic dermatitis biomarkers highlights the systemic nature of the disease. J Invest Dermatol. 2017;137(3):603-613.
6. Simpson EL, et al. Two phase 3 trials of dupilumab versus placebo in atopic dermatitis. N Engl J Med. 2016;375(24):2335-2348.

Educational Objectives

After completing this activity, the participant should be better able to:

• Discuss pathophysiologic mechanisms and risk factors that contribute to atopic dermatitis development and persistence, including potential treatment targets
• Evaluate patients with atopic dermatitis over time for persistent symptoms, comorbidities, and treatment responses
• Describe the clinical profiles of current and emerging biologic therapies for moderate-to-severe atopic dermatitis
• Tailor long-term therapy for moderate-to-severe atopic dermatitis to prevent exacerbations, maximize health-related quality of life, manage comorbidities, and minimize adverse events
• Educate patients and caregivers to improve their understanding of atopic dermatitis, provide Action Plans to reduce exacerbations, and promote shared decision-making

Physician Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Integritas Communications. Global is accredited by the ACCME to provide continuing medical education for physicians.

This CME/CE activity complies with all requirements of the federal Physician Payment Sunshine Act. If a reportable event is associated with this activity, the accredited provider managing the program will provide the appropriate physician data to the Open Payments database.

Physician Credit Designation

Global Education Group designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

EACCME Accreditation Statement

The Looking Beneath the Surface in Atopic Dermatitis: Targeting Dysregulation and Delivering Comprehensive Care, Geneva, Switzerland, 15/09/2017 - 15/09/2017 has been accredited by the European Accrediation Council for Continuing Medical Educatioi (EACCME^®) with 1 European CME credits (ECMEC^®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physcians may convert convert EACCME® credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME® credit to AMA credit can be found at www.ama-assn.org/go/internationalcme

Disclosure of Conflicts of Interest

Global Education Group (Global) requires instructors, planners, managers, and other individuals and their spouses/life partners who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

Americans with Disabilities Act

Event staff will be glad to assist you with any special needs (ie, physical, dietary, etc). Please contact Mike Remsen prior to the live event at mremsen@integritasgrp.com.

For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.