
Minimizing Patient Risks From COVID-19
An Update on Monoclonal Antibody Therapies
Meeting Slides

Clinical Practice Guidelines
COVID-19 Treatment Guidelines.
National Institutes of Health
Clinician Resources
Federal response to COVID-19: monoclonal antibody clinical implementation guide.
Department of Health and Human Services (DHHS).
Assistant Secretary for Preparedness and Response’s response to COVID-19.
DHHS.
Emergency Use Authorization of Bamlanivimab and Etesevimab.
US Food and Drug Administration (FDA).
Emergency Use Authorization of REGEN-COV™ (casirivimab/imdevimab).
FDA.
Emergency Use Authorization of Sotrovimab.
FDA.
Suggested Readings
Effect of bamlanivimab vs placebo on incidence of COVID-19 among residents and staff of skilled nursing and assisted living facilities: a randomized clinical trial.
Cohen MS, Nirula A, Mulligan MJ, et al. JAMA. 2021;326(1):46-55.
Effect of bamlanivimab as monotherapy or in combination with etesevimab on viral load in patients with mild to moderate COVID-19: a randomized clinical trial.
Gottlieb RL, Nirula A, Chen P, et al. JAMA. 2021;325(7):632-644.
Early Covid-19 treatment with SARS-CoV-2 neutralizing antibody sotrovimab.
Gupta A, Gonzalez-Rojas Y, Juarez E, et al. medRxiv. 2021. [Epub ahead of print].
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor.
Lan J, Ge J, Yu J, et al. Nature. 2020;581(7807):215-220.
Subcutaneous REGEN-COV antibody combination to prevent Covid-19.
O’Brien MP, Forleo-Neto E, Musser BJ, et al. N Engl J Med. 2021;385(13):1184-1195.
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group, Horby PW, Mafham M, Peto L, et al. medRxiv. 2021. [Epub ahead of print].
Racial bias in pulse oximetry measurement.
Sjoding MW, Dickson RP, Iwashyna TJ, Gay SE, Valley TS. N Engl J Med. 2020;383(25):2477-2478.
REGEN-COV antibody combination and outcomes in outpatients with Covid-19.
Weinreich DM, Sivapalasingam S, Norton T, et al. N Engl J Med. 2021. [Epub ahead of print].
An Update on Monoclonal Antibody Therapies
An Update on Monoclonal Antibody Therapies
An Update on Monoclonal Antibody Therapies
An Update on Monoclonal Antibody Therapies
Relevant Resources
Differential Diagnosis and Comprehensive Management Strategies
Optimizing Maintenance Therapy Across Healthcare Settings
Improving Outcomes for Patients with COPD
Collaborative Approaches to Guideline-Concordant Patient Care
New Strategies for Individualizing Long-term Care
A New Era in Precision Medicine
Evolving Best Practices to Optimize Outcomes
Consensus and Controversies on the Road to Precision Medicine
The PCPs Role in Preventing HIV
Ongoing Monitoring, Pulmonary Rehabilitation, and Individualized Care
What Do You Know About PrEP?
Optimizing Use of Clinical Evidence & Pharmacoeconomic Models in Managed Care
What Do You Know About PrEP?
Got it? Treat it!
Debates and Discussions About Personalizing Patient Management
The Critical Role of the Community Pharmacist
Bringing Local Communities Together to Eliminate Coinfection Through Knowledge and Partnerships.
Volume 1: Rapid ART Initiation: A New Addition to the HIV-Care Tool Box
Differential Diagnosis, Multidisciplinary Management, and Patient Engagement
Key Issues Impacting OB/GYN Practice
From Guideline Recommendations to Daily Clinical Decision-Making
Hot Topics in HBV, HCV, and NASH
Improving Patient Outcomes Through Shared Clinical Decision Making
Volume II: Expanding Evidence for the Role of Rapid ART Initiation in HIV Practice
Why It Matters in OB/GYN Practice Today
Improving Patient Outcomes Through Shared Clinical Decision Making
Digging Deep on Shared Decision-Making
A Treater’s Guide to Optimizing Care in the Aging Patient with Comorbidities
How the Pharmacist Can Make a Difference
HIV Can Be Prevented— Are You Doing Your Part?
Rapid Start ART — A New Model for HIV Care
Clinical Resource Center
Understanding the Growing Syndemic — Opioids, HCV, and HIV
A Case-Based Conversation on Managing Asthma and Chronic Rhinosinusitis With Nasal Polyposis
The Clinical and Utilization Benefits of Exacerbation Prevention
Mechanistic Insights and Emerging Treatment Options
A PrEP Primer
A Focus on Exacerbation Prevention
Best Practices for Primary Care
The PCP’s Role in HCV Elimination
What the Pharmacist Needs to Know about PrEP
The Rapid ART Standard of Care: From Evidence to Healthcare Equity
Maximizing Your Role to Impact Patient Outcomes
Evolving Best Practices for Patient Management
Building Bridges to Reach People Who Inject Drugs With the Goal to Eliminate HCV
Benefits, Barriers, & Best Practices in an Advancing Field
Practical Solutions Across the Spectrum of Care
Informing the Future of NASH Diagnosis and Assessment
A PEP/PrEP Training Guide for Pharmacists
Shared Decision-making in the Era of Biologics
New Pathways to Patient Management
From Comprehensive Patient Evaluations to Individualized Evidence-based Care
Preventing COPD Exacerbations to Improve Outcomes
A Critical Step Toward HCV Elimination
Considering the Patient, the Provider, and the Science
A Multidisciplinary Online Mini-Curriculum
A Whole Patient Case Series
Debates and Discussions about Monoclonal Antibody Therapies
New Avenues to the Management of Severe Asthma
Establishing Clinical Readiness Through Mentored Learning
Evolving Best Practices for Pediatric Patients
Interdisciplinary Strategies for Adult and Pediatric Patients
Interdisciplinary Management of Eosinophilic Esophagitis and Hereditary Angioedema
Reducing LDL-C and a Lifetime of Cardiovascular Risk
A Multidisciplinary Look at Early Diagnosis and Management
Finding the Path in Chronic Rhinosinusitis with Nasal Polyps
Recent Developments in Anti-SARS-CoV-2 Monoclonal Antibodies for Treatment
Best Practices for Diagnosis and Management
An Update on Best Practices
New Avenues to Pre-Exposure Prophylaxis
New Pathways to Optimize Patient Outcomes
An Updated Clinician’s Guide to Assessment and Management
Debates and Discussions About New Upstream Treatment Avenues
A Case-Based Update on Pediatric Patients
What the Pharmacist Needs to Know
A Look at the Changing HIV Playing Field
A “How To” Series Spanning Policy to Practice
Test Your Mastery!
Building Bridges to Reach People who Inject Drugs with the Goal of Employing PrEP for HIV Prevention
Bringing HIV Prevention to a New Level
Optimizing HIV Prevention in Primary Care
Monoclonal Antibodies for the Prevention and Treatment of COVID-19
Exploring New Treatment Avenues in Nonadvanced Systemic Mastocytosis
Practical Updates on the 2023 GOLD Guidelines
A Phone-a-Friend CME Series – Volume 2
Best Practices for Screening, Diagnosis, and Management
Incorporating New Data and Updated Guidelines Into Daily Practice
From the Airway Epithelium to Improved Patient Outcomes
Exercising Best Practices for Hospitalized Patients
Accelerating Diagnosis and Treatment