HCV Updates and Insights
Clinical Practice Guidelines
Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living With HIV.
US Department of Health and Human Services, 2017 (last updated October 2018).
Evaluation and Management of Chronic Hepatitis C Virus (HCV) Infection.
Federal Bureau of Prisons Clinical Guidance. 2018.
HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C.
American Association for the Study of Liver Diseases/Infectious Diseases Society of America (AASLD/IDSA), 2017.
Clinical Resources
Harm Reduction Coalition.
HEP Drug Interactions.
University of Liverpool, 2019.
Opioid Overdose Prevention Toolkit.
Substance Abuse and Mental Health Services Administration (SAMHSA).
Suggested Readings
Direct-acting antivirals improve access to care and cure for patients with HIV and chronic HCV infection.
Collins LF, et al. Open Forum Infect Dis. 2018;5(1):ofx264.
Opportunities for treatment of the hepatitis C virus-infected patient with chronic kidney disease.
Ladino M, et al. World J Hepatol. 2017;9(19):833-839.
Universal opt-out screening for hepatitis C virus (HCV) within correctional facilities is an effective intervention to improve public health.
Morris MD, et al. Int J Prison Health. 2017;13(3-4):192-199.
Retention in buprenorphine treatment is associated with improved HCV care outcomes.
Norton BL, et al. J Subst Abuse Treat. 2017;75:38-42.
The syndemic of opioid misuse, overdose, HCV, and HIV: structural-level causes and interventions.
Perlman DC, Jordan AE. Curr HIV/AIDS Rep. 2018;15(2):96-112.
Primary care for persons who inject drugs.
Visconti AJ, et al. Am Fam Physician. 2019;99(2):109-116.
Risk factors for hepatitis C virus reinfection after sustained virologic response in patients coinfected with HIV.
Young J, et al. Clin Infect Dis. 2017;64(9):1154-1162.
Action and Advocacy
EDUCATION AND TRAINING
Health literacy and liver disease.
Gulati R, et al. Clin Liver Dis. 2018;11(2):48-51.
Hepatitis Education Project.
The Hepatitis Education Project provides support, education, advocacy, and direct services for people affected by hepatitis, and works to raise hepatitis awareness among patients, medical providers, and the general public.
National Hepatitis Corrections Network.
The National Hepatitis Corrections Network (NHCN) supports a public health approach to hepatitis education, prevention, testing, and treatment in prisons and jails.
Project ECHO (Extension for Community Healthcare Outcomes).
Project ECHO is a collaborative, telecommunications-based model of medical education and care management designed to train primary care clinicians to provide specialty care in rural and underserved areas.
PUBLIC POLICY: EXPANSION OF ACCESS TO CARE
Drug purchasing strategies to treat people with hepatitis C in the criminal justice system.
Akiyama MJ, et al. Am J Public Health. 2018;108(5):607-608.
Center for Health Law and Policy Innovation of Harvard Law School (CHLPI) and National Viral Hepatitis Roundtable (NVHR).
Together, CHLPI and NVHR continue to play a pivotal role in removing Medicaid restrictions on HCV treatment. An interactive map allows you to see each state’s Medicaid restrictions. Last updated November 2018.
Expansion of treatment for hepatitis C virus infection by task shifting to community-based nonspecialist providers: a nonrandomized clinical trial.
Kattakuzhy S, et al. Ann Intern Med. 2017;167(5):311-318.
SUPPORT-SERVICES NETWORKING
North American Syringe Exchange Network (NASEN).
NASEN provides a directory of syringe exchange programs that can be located by zip code, landmark, city, or state.
SAMHSA: Behavioral Health Treatment Services Locator.
SAMHSA provides confidential and anonymous information on substance abuse and mental health treatment facilities throughout the United States and its territories.
SAMHSA: Medication-Assisted Treatment (MAT) Support Organizations.
SAMHSA provides numerous links to nonprofit associations, federal agencies, and patient groups that offer support for providers of medication-assisted treatment (MAT), as well as their patients and families.
Patient Resources
Hepatitis C Information Center
American Liver Foundation, 2018.
The American Liver Foundation’s Hepatitis C Information Center website is a dedicated online information and resource center created in support of individuals impacted by HCV infection.
Project Inform
Project Inform provides up-to-date information to help people living with HIV and HCV make the best choices regarding their treatment and care.
Appendix
Complete List of References Associated With Figure Titled Real-World Evidence.
Conway B, et al. American Association for the Study of Liver Diseases. The Liver Meeting® 2016 – AASLD. November 11−15, 2016; Boston, MA. Poster 1992.
Dore GJ, et al. Ann Intern Med. 2016;165(9):625-634.
Drugs@FDA. 2018. https://www.accessdata.fda.gov/scripts/cder/daf/.
Grebely J, et al. Clin Infect Dis. 2016;63(11):1405-1411.
Grebely J, et al. Clin Infect Dis. 2016;63(11):1479-1481.
Grebely J, et al. J Hepatol. 2017;66:S513-S514.
Kiser JJ. Top Antivir Med. 2016;24(3):106-110.
Naggie SD, et al. N Engl J Med. 2015;373(8):705-713.
Osinusi A, et al. JAMA. 2015;313(12):1232-1239.
Puoti M, et al. J Hepatol. 2018;69(2):293-300.
Rockstroh JK, et al. Clin Infect Dis. 2018;67(7):1010-1017.
Rockstroh JK, et al. Lancet HIV. 2015;2(8):e319-e327.
Rockstroh JK. European Association for the Study of the Liver. The International Liver Congress™ − EASL 2017. April 19-23, 2017; Amsterdam, The Netherlands.
Sulkowski MS, et al. JAMA. 2015;313(12):1223-1231.
Wyles D, et al. Clin Infect Dis. 2017;65(1):6-12.
Zeuzem S, et al. Ann Intern Med. 2015;163(1):1-13.
Realities, Challenges, and Opportunities to Improve Care
Relevant Resources
The PCPs Role in Preventing HIV
What Do You Know About PrEP?
Optimizing Use of Clinical Evidence & Pharmacoeconomic Models in Managed Care
Advances in the Diagnosis and Treatment of Nonalcoholic Steatohepatitis
What Do You Know About PrEP?
Got it? Treat it!
The Critical Role of the Community Pharmacist
Bringing Local Communities Together to Eliminate Coinfection Through Knowledge and Partnerships.
Volume 1: Rapid ART Initiation: A New Addition to the HIV-Care Tool Box
The Emerging Role of the Diabetologist
Key Issues Impacting OB/GYN Practice
An Interactive Experience Highlighting Recent Clinical Advances
Hot Topics in HBV, HCV, and NASH
Emerging Concepts in Patient Management
Building Your Understanding to Combat a Growing Problem
Volume II: Expanding Evidence for the Role of Rapid ART Initiation in HIV Practice
Why It Matters in OB/GYN Practice Today
A Treater’s Guide to Optimizing Care in the Aging Patient with Comorbidities
How the Pharmacist Can Make a Difference
HIV Can Be Prevented— Are You Doing Your Part?
Rapid Start ART — A New Model for HIV Care
Understanding the Growing Syndemic — Opioids, HCV, and HIV
Appraising the Therapeutic Armamentarium in Moderate and Severe Disease
A PrEP Primer
The PCP’s Role in HCV Elimination
What the Pharmacist Needs to Know about PrEP
The Rapid ART Standard of Care: From Evidence to Healthcare Equity
Maximizing Your Role to Impact Patient Outcomes
Building Bridges to Reach People Who Inject Drugs With the Goal to Eliminate HCV
Benefits, Barriers, & Best Practices in an Advancing Field
Practical Solutions Across the Spectrum of Care
Informing the Future of NASH Diagnosis and Assessment
A PEP/PrEP Training Guide for Pharmacists
An Interactive Learning Experience
A Focus on Clinical Evidence and Guideline Recommendations
A Critical Step Toward HCV Elimination
Considering the Patient, the Provider, and the Science
A Multidisciplinary Online Mini-Curriculum
Volume 1: A Guided Tour of the Evidence Driving Selection of First-line Advanced Therapies in Moderate to Severe IBD
Debates and Discussions about Monoclonal Antibody Therapies
An Update on Monoclonal Antibody Therapies
Establishing Clinical Readiness Through Mentored Learning
Interdisciplinary Strategies for Adult and Pediatric Patients
Interdisciplinary Management of Eosinophilic Esophagitis and Hereditary Angioedema
A Multidisciplinary Look at Early Diagnosis and Management
Recent Developments in Anti-SARS-CoV-2 Monoclonal Antibodies for Treatment
Best Practices for Diagnosis and Management
An Update on Best Practices
New Avenues to Pre-Exposure Prophylaxis
An Updated Clinician’s Guide to Assessment and Management
What the Pharmacist Needs to Know
A Look at the Changing HIV Playing Field
A “How To” Series Spanning Policy to Practice
Test Your Mastery!
Building Bridges to Reach People who Inject Drugs with the Goal of Employing PrEP for HIV Prevention
Bringing HIV Prevention to a New Level
Optimizing HIV Prevention in Primary Care
Monoclonal Antibodies for the Prevention and Treatment of COVID-19
A Multidisciplinary Approach
Exploring New Treatment Avenues in Nonadvanced Systemic Mastocytosis
A Phone-a-Friend CME Series – Volume 2
Incorporating New Data and Updated Guidelines Into Daily Practice
Exercising Best Practices for Hospitalized Patients
