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HIV Experts & Evidence™

Evolving Models of HIV Care

Volume II: Expanding Evidence for the Role of Rapid ART Initiation in HIV Practice

Meeting Slides

Clinical Practice Guidelines

Guidelines for Managing Advanced HIV Disease and Rapid Initiation of Antiretroviral Therapy.

World Health Organization, 2017.

Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living With HIV.

US Department of Health and Human Services, 2017 (last updated March 2019).

HIV Testing Guidelines.

Centers for Disease Control and Prevention (CDC), 2018.

Clinical Resources

90–90–90: An Ambitious Treatment Target to Help End the AIDS Epidemic.

Joint United Nations Programme on HIV/AIDS (UNAIDS), 2014.

AIDSVu.

Emory University Rollins School of Public Health, Gilead Sciences, Inc., and the Center for AIDS Research at Emory University (CFAF), 2018.

AtlasPlus Presentation Slides: HIV Diagnoses by County, 2014.

National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.

Database of Antiretroviral Drug Interactions.

HIV InSite. University of California, San Francisco, 2018.

Harm Reduction Coalition.

 

HEP Drug Interactions.

University of Liverpool, last reviewed March 2019.

Status of State Medicaid Expansion Decisions: Interactive Map.

Kaiser Family Foundation, 2019.

Suggested Readings

Effects of a multicomponent intervention to streamline initiation of antiretroviral therapy in Africa: a stepped-wedge cluster-randomised trial.

Amanyire G, et al. Lancet HIV. 2016;3(11):e539-e548.

RAPID ART: high virologic suppression rates with immediate ART initiation in a vulnerable urban clinic population.

Coffey S, et al. AIDS. 2018. [Epub ahead of print]

Antiretroviral therapy for the prevention of HIV-1 transmission.

Cohen MS, et al. N Engl J Med. 2016;375(9):830-839.

Prevention of HIV-1 infection with early antiretroviral therapy.

Cohen MS, et al. N Engl J Med. 2011;365(6):493-505.

A rapid entry program in the South: improving access to care and time to viral suppression.

Colasanti J, et al. 25th Conference on Retroviruses and Opportunistic Infections (CROI) 2018; March 4−7, 2018; Boston, MA. Poster 1109.

Continuous retention and viral suppression provide further insights into the HIV care continuum compared to the cross-sectional HIV care cascade.

Colasanti J, et al. Clin Infect Dis. 2016;62(5):648-654.

HIV viral load and transmissibility of HIV infection: undetectable equals untransmittable.

Eisinger RW, et al. JAMA. 2019;321(5):451-452.

Linkage and antiretroviral therapy within 72 hours at a federally qualified health center in New Orleans.

Halperin J, et al. AIDS Patient Care STDS. 2018;32(2):39-41.

Rapid HIV care cuts time to viral suppression in half.

Schoen J, Gallagher G. Healio Infect Dis News. 2018.

Initiation of antiretroviral therapy in early asymptomatic HIV infection.

INSIGHT START Study Group. N Engl J Med. 2015;373(9):795-807.

Same-day HIV testing with initiation of antiretroviral therapy versus standard care for persons living with HIV: a randomized unblinded trial.

Koenig SP, et al. PLoS Med. 2017;14(7):e1002357.

Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho: the CASCADE randomized clinical trial.

Labhardt ND, et al. JAMA. 2018;319(11):1103-1112.

Association of implementation of a universal testing and treatment intervention with HIV diagnosis, receipt of antiretroviral therapy, and viral suppression in East Africa.

Petersen M, et al. JAMA. 2017;317(21):2196-2206.

The effect of same-day observed initiation of antiretroviral therapy on HIV viral load and treatment outcomes in a U.S. public health setting.

Pilcher CD, et al. J Acquir Immune Defic Syndr. 2017;74(1):44-51.

Initiating antiretroviral therapy for HIV at a patient’s first clinic visit: the RapIT randomized controlled trial.

Rosen S, et al. PLoS Med. 2016;13(5):e1002015.

Trends in the San Francisco human immunodeficiency virus epidemic in the "Getting to Zero" era.

Scheer S, et al. Clin Infect Dis. 2018;66(7):1027-1034.

A trial of early antiretrovirals and isoniazid preventive therapy in Africa.

TEMPRANO ANRS 12136 Study Group. N Engl J Med. 2015;373(9):808-822.

Pooled week 48 efficacy and baseline resistance: B/F/TAF in treatment-naïve patients.

White K, et al. CROI 2018. March 4−7, 2018; Boston, MA. Abstract 532.

Patient Resources

Centers for Disease Control and Prevention (CDC): HIV Basics

The CDC is a division within the US Department of Health and Human Services (DHHS), the principal agency for protecting the health of all Americans. This comprehensive site provides extensive links to topics across the HIV-care continuum, including PrEP.

Project Inform

Project Inform provides up-to-date information to help people living with HIV and HCV make the best choices regarding their treatment and care.

Hepatitis C and HIV Co-infection Booklets

Sex-C: Sex and Hepatitis C Prevention Tips for Gay Men

Sexual Transmission of Hepatitis C: A Guide for HIV-Positive Gay Men

 

Positively Aware

Positively Aware, created by TPAN (Test Positive Aware Network), is a source of HIV-treatment news for consumers, as well as an educational tool for HIV caregivers. The site features PrEP resources, including videos for MSM and transgender people.

Smartphone Pill-Reminder Apps (Free)

Mango Health — Medicine Reminder and Manager for iPhone

Mango Health for Android

Medisafe Pill Reminder and Alarm for iPhone

Medisafe Pill Reminder and Medication Tracker for Android

Relevant Resources

Acute Management of Migraine Attacks

Overcoming Pain and Gastrointestinal Distress to Improve Patient Outcomes

Clinical Updates on the Management of Gout

Evidence-Based Strategies for Improved Patient Outcomes

Opioid-Induced Constipation

Proactive Diagnosis and Targeted Management

Chronic Obstructive Pulmonary Disease, Asthma, or Both

Differential Diagnosis and Comprehensive Management Strategies

Improving Outcomes in Chronic Obstructive Pulmonary Disease

Optimizing Maintenance Therapy Across Healthcare Settings

Managing Gout in Primary Care

Evolving Strategies for Diagnosis and Long-Term Management

Clinical Issues in Chronic Pain

Consensus and Controversies for Responsible Opioid Prescribing

Noninsulin Approaches to Managing Type 2 Diabetes

Best Practices in Combination Therapy

Hitting the Target in Type 2 Diabetes

Evolving Approaches to Insulin Based Therapy

Clearing the Air

Improving Outcomes for Patients with COPD

Clinical Updates in Type 2 Diabetes

New Strategies for Insulin Replacement Therapy

How Low Do You Go?

Clinical Updates in LDL-C Management

Incretin-Based Therapies For Type 2 Diabetes

Improving Comprehensive Patient Care

Improving Outcomes in Non–24-Hour Sleep-Wake Disorder

Identifying Patients and Tailoring Therapy

Comprehensive Management of Chronic Obstructive Pulmonary Disease

Collaborative Approaches to Guideline-Concordant Patient Care

Clinical Updates in the Management of Severe Asthma

New Strategies for Individualizing Long-term Care

Comprehensive Chronic Pain Management

A Focus on Patients With Opioid-Induced Constipation

Clinical Issues in Bipolar Depression

Consensus and Controversies Across the Spectrum of Patient Presentations

Clinical Updates in Rheumatoid Arthritis

Evolving Treatment Algorithms and Expert Perspectives on Biosimilars

Caring for Patients with Severe Asthma

Evolving Best Practices to Optimize Outcomes

PrEP for Your Patients’ Needs

The PCPs Role in Preventing HIV

BRIDGE HCV

Building Bridges to Reach People Who Inject Drugs With the Goal to Eliminate HCV

Can You Spot Axial Spondyloarthritis?

The PCP’s Role in Timely Recognition and Referral

Value-Based HIV Formularies

Optimizing Use of Clinical Evidence & Pharmacoeconomic Models in Managed Care

Hepatitis C is Curable

Got it? Treat it!

Real-World Issues in HIV Prevention & Treatment

The Critical Role of the Community Pharmacist

BLOCK HIV/HCV

Bringing Local Communities Together to Eliminate Coinfection Through Knowledge and Partnerships.

Evolving Models of HIV Care

Volume 1: Rapid ART Initiation: A New Addition to the HIV-Care Tool Box

Advancing the Care of Severe Asthma

Differential Diagnosis, Multidisciplinary Management, and Patient Engagement

Updates in HCV Screening and Treatment

Key Issues Impacting OB/GYN Practice

Clinical Issues in Chronic Liver Disease

Hot Topics in HBV, HCV, and NASH

Assessing Your Patients for HCV and HIV

Why It Matters in OB/GYN Practice Today

HIV as a Chronic Disease

A Treater’s Guide to Optimizing Care in the Aging Patient with Comorbidities

The Pursuit of Hepatitis C Elimination

How the Pharmacist Can Make a Difference