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HIV in Aging Patients eHealth Source™

HIV as a Chronic Disease

A Treater’s Guide to Optimizing Care in the Aging Patient with Comorbidities

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Clinical Practice Guidelines

Recommendations for evaluation and management of bone disease in HIV.

Brown TT, Hoy J, Borderi M, et al. Clin Infect Dis. 2015;60(8):1242-1251.

Primary care guidelines for the management of persons infected with HIV: 2013 update by the HIV Medicine Association of the Infectious Diseases Society of America.

Aberg JA, Gallant JE, Ghanem KG, Emmanuel P, Zingman BS, Horberg MA. Clin Infect Dis. 2013;58(1):e1-e34.

Preventive medicine. 

Medical Care Criteria Committee.

Practice bulletin no. 167: gynecologic care for women and adolescents with human immunodeficiency virus.

American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins–Gynecology. Obstet Gynecol. 2016;128(4):e89-e110.

Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV

US Department of Health and Human Services.

KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease.

Eknoyan G, Lameire N, Eckardt K, et al. Kidney Int. 2013;3(1):5-14.

Patient and Caregiver Resources

AIDS Map Resources

NAM Publications

Resources for Persons Living with HIV

Centers for Disease Control and Prevention

HIV Resources

National Institutes of Health

Suggested Readings

Comparison of risk and age at diagnosis of myocardial infarction, end-stage renal disease, and non-AIDS-defining cancer in HIV-infected versus uninfected adults.

Althoff KN, McGinnis KA, Wyatt CM, et al. Clin Infect Dis. 2015;60(4):627-638.

Brief report: randomized, double-blind comparison of tenofovir alafenamide (TAF) vs tenofovir disoproxil fumarate (TDF), each coformulated with elvitegravir, cobicistat, and emtricitabine (E/C/F) for initial HIV-1 treatment: week 144 results.

Arribas JR, Thompson M, Sax PE, et al. J Acquir Immune Defic Syndr. 2017;75(2):211-218.

Cardiovascular disease (CVD) and chronic kidney disease (CKD) event rates in HIV-positive persons at high predicted CVD and CKD risk: A prospective analysis of the D:A:D observational study.

Boyd MA, Mocroft A, Ryom L, et al. PLoS Med. 2017;14(11):e1002424.

Body composition, soluble markers of inflammation, and bone mineral density in antiretroviral therapy-naive HIV-1-infected individuals.

Brown TT, Chen Y, Currier JS, et al. J Acquir Immune Defic Syndr. 2013;63(3):323-330.

Management of HIV/AIDS in older patients-drug/drug interactions and adherence to antiretroviral therapy.

Burgess MJ, Zeuli JD, Kasten MJ. HIV AIDS. 2015;7:251-264.

Kidney diseases associated with human immunodeficiency virus infection.

Cohen SD, Kopp JB, Kimmel PL. N Engl J Med. 2017;377(24):2363-2374.

Systematic review and meta-analysis: renal safety of tenofovir disoproxil fumarate in HIV-infected patients.

Cooper RD, Wiebe N, Smith N, Keiser P, Naicker S, Tonelli M. Clin Infect Dis. 2010;51(5):496-505.

Superior efficacy and improved renal and bone safety after switching from a tenofovir disoproxil fumarate- to a tenofovir alafenamide-based regimen through 96 weeks of treatment.

DeJesus E, Haas B, Segal-Maurer S, et al. AIDS Res Hum Retroviruses. 2018;34(4):337-342.

Cardiac dysfunction among people living with HIV: a systematic review and meta-analysis.

Erqou S, Lodebo BT, Masri A, et al. JACC Heart Fail. 2019;7(2):98-108.

Immediate initiation of antiretroviral therapy for HIV infection accelerates bone loss relative to deferring therapy: findings from the START bone mineral density substudy, a randomized trial.

Hoy JF, Grund B, Roediger M, et al. J Bone Miner Res. 2017;32(9):1945-1955.

Initiation of antiretroviral therapy in early asymptomatic HIV infection.

INSIGHT START Study Group, Lundgren JD, Babiker AG, et al. New Engl J Med. 2015;373(9):795-807.

Factors associated with chronic renal failure in HIV-infected ambulatory patients.

Krawczyk CS, Holmberg SD, Moorman AC, Gardner LI, McGwin GJ, HIV Outpatient Study Group. AIDS. 2004;18(16):2171-2178.

Vascular disease and aging in HIV: time to extend the treatment cascade.

Longenecker CT. Vasc Med. 2018;23(5):476-477.

Long-term efavirenz use is associated with worse neurocognitive functioning in HIV-infected patients.

Ma Q, Vaida F, Wong J, et al. J Neurovirol. 2016;22(2):170-178.

Human immunodeficiency virus-associated neurocognitive disorders: Mind the gap.

McArthur JC, Steiner J, Sacktor N, Nath A. Ann Neurol. 2010;67(6):699-714.

Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial.

Molina JM, Squires K, Sax PE, et al. Lancet HIV. 2018;5(5):e211-e220.

Screening for anal cancer in women.

Moscicki AB, Darragh TM, Berry-Lawhorn JM, et al. J Low Genit Tract Dis. 2015;19(3 Suppl 1):S27-42.

Ageing and inflammation in patients with HIV infection.

Nasi M, De Biasi S, Gibellini L, et al. Clin Exp Immunol. 2017;187(1):44-52.

Prevalence of non-HIV cancer risk factors in persons living with HIV/AIDS: a meta-analysis.

Park LS, Hernández-Ramírez RU, Silverberg MJ, Crothers K, Dubrow R. AIDS. 2016;30(2):273-291.

The hidden burden of fractures in people living with HIV.

Premaor MO, Compston JE. JBMR Plus. 2018;2(5):247-256.

Time trends for risk of severe age-related diseases in individuals with and without HIV infection in Denmark: a nationwide population-based cohort study.

Rasmussen LD, May MT, Kronborg G, et al. Lancet HIV. 2015;2(7):e288-298.

Tenofovir alafenamide vs. tenofovir disoproxil fumarate in single tablet regimens for initial HIV-1 therapy: a randomized phase 2 study.

Sax PE, Zolopa A, Brar I, et al. J Acquir Immune Defic Syndr. 2014;67(1):52-58.

HIV-associated neurocognitive disorder--pathogenesis and prospects for treatment.

Saylor D, Dickens AM, Sacktor N, et al. Nat Rev Neurol. 2016;12(4):234-248.

Efficacy and safety of antiretrovirals in HIV-infected patients with cancer.

Torres HA, Rallapalli V, Saxena A, et al. Clin Microbiol Infect. 2014;20(10):O672-O679.

HIV and ischemic heart disease.

Vachiat A, McCutcheon K, Tsabedze N, Zachariah D, Manga P. J Am Coll Cardiol. 2017;69(1):73-82.

Recommendations for Managing Drug-Drug Interactions with Statins and HIV Medications.

Wiggins BS, Lamprecht DG, Jr., Page RL, 2nd, Saseen JJ. Am J Cardiovasc Drugs. 2017;17(5):375-389.

HIV and aging.

Wing EJ. Int J Infect Dis. 2016;53:61-68.

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HIV in Aging Patients eHealth Source™

HIV as a Chronic Disease: A Treater’s Guide to Optimizing Care in the Aging Patient with Comorbidities

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