Suggested Readings

Mechanism-based treatment strategies for IBD: cytokines, cell adhesion molecules, JAK inhibitors, gut flora, and more.

Schreiner P, et al. Inflamm Intest Dis. 2019;4(3):79-96.

From bench to bedside: fecal calprotectin in inflammatory bowel diseases clinical setting.

Mumolo MG, et al. World J Gastroenterol. 2018;24(33):3681-3694.

The role of laboratory tests in Crohn’s disease.

Cappello M, Morreale GC. Clin Med Insights Gastroenterol. 2016;9:51-62.

A treat-to-target update in ulcerative colitis: a systematic review.

Ungaro R, et al. Am J Gastroenterol. 2019;114(6):874-883.

Involvement of JAK/STAT signaling in the pathogenesis of inflammatory bowel disease.

Coskun M, et al. Pharmacol Res. 2013;76:1-8.

JAK selectivity for inflammatory bowel disease treatment: does it clinically matter?

Danese S, et al. Gut. 2019;68(10):1893-1899.

Safety of Janus kinase inhibitors in patients with inflammatory bowel diseases or other immune-mediated diseases: a systematic review and meta-analysis.

Olivera PA, et al. Gastroenterology. 2020;158(6):1554-1573.

Tofacitinib as induction and maintenance therapy for ulcerative colitis.

Sandborn WJ, et al. N Engl J Med. 2017;377(5):496-497.

SELECTION: filgotinib for ulcerative colitis.

Brierley R. Lancet Gastroenterol Hepatol. 2020;5(12):1036-1037.

Clinical remission in patients with moderate-to-severe Crohn’s disease treated with filgotinib (the FITZROY study): results from a phase 2, double-blind, randomised, placebo-controlled trial.

Vermeire S, et al. Lancet. 2017;389(10066):266-275.

Efficacy and safety of upadacitinib in a randomized trial of patients with Crohn's disease.

Sandborn WJ, et al. Gastroenterology. 2020;158(8):2123-2138.

Efficacy of upadacitinib in a randomized trial of patients with active ulcerative colitis.

Sandborn WJ, et al. Gastroenterology. 2020;158(8):2139-2149.

Patient Resources

American College of Gastroenterology

American Gastroenterological Association

Crohn’s and Colitis Foundation

European Crohn’s and Colitis Organisation

National Institute of Diabetes and Digestive and Kidney Diseases

Health Information for Crohn’s Disease

Health Information for Ulcerative Colitis

Linked Resources

ACG Clinical Guidelines: Management of Crohn's Disease in Adults.

Lichtenstein GR, et al. Am J Gastroenterol. 2018;113(4):481-517.

ECCO Guidelines on Therapeutics in Crohn's Disease: Medical Treatment.

Torres J, et al. J Crohns Colitis. 2020;14(1):4-22.

ACG Clinical Guideline: Ulcerative Colitis in Adults.

Rubin DT, et al. Am J Gastroenterol. 2019;114(3):384-413.

AGA Clinical Practice Guideline on the Management of Moderate to Severe Ulcerative Colitis.

Feuerstein JD, et al. Gastroenterology. 2020;158(5):1450-1461.

ACG Clinical Guideline: Preventive Care in Inflammatory Bowel Disease.

Farraye F, et al. Am J Gastroenterol. 2017;112(2):241-258.