Lifting the Burdens of Idiopathic Hypersomnia
Accelerating Diagnosis and Individualizing Management
Idiopathic hypersomnia.
Trotti LM. Sleep Med Clin. 2017;12(3):331-344.
Disease symptomatology and response to treatment in people with idiopathic hypersomnia: initial data from the hypersomnia foundation registry.
Trotti LM, et al. Sleep Med. 2020;75:343-349.
Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.
Maski K, et al. J Clin Sleep Med. 2021;17(9):1895-1945.
Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine clinical practice guideline.
Maski K, et al. J Clin Sleep Med. 2021;17(9):1881-1893.
Symptom severity and treatment satisfaction in patients with idiopathic hypersomnia: the real world idiopathic hypersomnia outcomes study (ARISE).
Schneider LD, et al. Nat Sci Sleep. 2023;15:89-101.
Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study.
Dauvilliers Y, et al. Lancet Neurol. 2022;21(1):53-65.
Long-term efficacy and safety of low-sodium oxybate in an open-label extension period of a placebo-controlled, double-blind, randomized withdrawal study in adults with idiopathic hypersomnia.
Morse AM, et al. J Clin Sleep Med. 2023;19(10):1811-1822.
Long-term safety and timing of adverse events with low-sodium oxybate in a phase 3 idiopathic hypersomnia study.
Bogan R, et al. Sleep. 2024;47(suppl 1):A273-A274.
GUIDELINES
The AASM International Classification of Sleep Disorders, Third Edition, Text Revision
American Academy of Sleep Medicine. The AASM International Classification of Sleep Disorders, Third Edition, Text Revision (ICSD-3-TR). Darien, IL: American Academy of Sleep Medicine; 2023.
Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Arlington, VA: American Psychiatric Association; 2013.
CLINICAL PRACTICE TOOLS AND RESOURCES
Epworth Sleepiness Scale (ESS)
Idiopathic Hypersomnia Sleep Severity (IHSS) Scale
North America Predictor of Sleepiness (NAPS) Scale
Lee-Chiong T. Sleep Med Clin. 2012;7: xv–xvi.
PATIENT RESOURCES AND ADVOCACY ORGANIZATIONS
Hypersomnia Foundation.
American Academy of Sleep Medicine (AASM).
National Sleep Foundation.
Project Sleep.
Lifting the Burdens of Idiopathic Hypersomnia
Accelerating Diagnosis and Individualizing Management
| Faculty: | Richard K. Bogan, MD, FCCP, FAASM; Karl Doghramji, MD, FAASM, DFAPA |
| Release: | 09/09/2024 |
| Expiration: | 09/09/2025 |
