
Finding Relief in Osteoarthritis
New Paths to Chronic Pain Management
Meeting Slides

Guidelines
Management of osteoarthritis of the hip: evidence-based clinical practice guidelines.
American Academy of Orthopaedic Surgeons. 2017.
Management of postoperative pain: a clinical practice guideline from the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' committee on regional anesthesia, executive committee, and administrative council.
Chou R, et al. J Pain. 2016;17(2):131-157.
Treatment of osteoarthritis of the knee: evidence-based guideline, 2nd edition.
Jevsevar DS. J Am Acad Orthop Surg. 2013;21(9):571-576.
2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee.
Kolasinski SL, et al. Arthritis Care Res (Hoboken). 2020;72(2):149-162.
Osteoarthritis: care and management in adults.
National Clinical Guideline Centre (UK). London: National Institute for Health and Care Excellence (UK); 2014
Patient Resources
American Chronic Pain Association
American College of Rheumatology
Centers for Disease Control and Prevention
Osteoarthritis Action Alliance
U.S. Pain Foundation
Clinical Assessment Tools
Hip Disability and Osteoarthritis Outcome Score (HOOS)
Knee Injury and Osteoarthritis Outcome Score (KOOS)
WOMAC Osteoarthritis Index
Suggested Readings
Safety of oral non-selective non-steroidal anti-inflammatory drugs in osteoarthritis: what does the literature say?
Cooper C, et al. Drugs Aging. 2019;36(Suppl 1):15-24.
The efficacy, tolerability, and joint safety of fasinumab in osteoarthritis pain: a phase iib/iii double-blind, placebo-controlled, randomized clinical trial.
Dakin P, et al. Arthritis Rheumatol. 2019;71(11):1824-1834.
Nerve growth factor and pain mechanisms.
Denk F, et al. Annu Rev Neurosci. 2017;40:307-325.
CDC guideline for prescribing opioids for chronic pain — United States, 2016.
Dowell D, et al. MMWR Recomm Rep. 2016;65(1):1-49.
Enhanced recovery protocols in total joint arthroplasty: a review of the literature and their implementation.
Galbraith AS, et al. Ir J Med Sci. 2018;187(1):97-109.
Gandhi R, et al. CMAJ. 2014;186(5):347‐355.
Surgical management of hip osteoarthritis.
Osteoarthritis.
Hunter DJ, Bierma-Zeinstra S. Lancet. 2019;393(10182):1745-1759.
Knee osteoarthritis: a review of management options.
Hussain SM, et al. Scott Med J. 2016;61(1):7‐16.
Efficacy and safety of oral NSAIDs and analgesics in the management of osteoarthritis: evidence from real-life setting trials and surveys.
Pelletier JP, et al. Semin Arthritis Rheum. 2016;45(suppl 4):S22-S27.
Effect of tanezumab on joint pain, physical function, and patient global assessment of osteoarthritis among patients with osteoarthritis of the hip or knee: a randomized clinical trial.
Schnitzer TJ, et al. JAMA. 2019;322(1):37-48.
Nonsurgical management of osteoarthritis knee pain in the older adult.
Taylor N. Clin Geriatr Med. 2017;33(1):41‐51.

Osteoarthritis Pathophysiology and Novel Treatment Targets
Presented by Jeffrey Gudin, MD
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