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Interactive Exchange

Finding Relief in Osteoarthritis

New Paths to Chronic Pain Management

Meeting Slides

Guidelines

Management of osteoarthritis of the hip: evidence-based clinical practice guidelines.

American Academy of Orthopaedic Surgeons. 2017.

Management of postoperative pain: a clinical practice guideline from the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' committee on regional anesthesia, executive committee, and administrative council.

Chou R, et al. J Pain. 2016;17(2):131-157.

Treatment of osteoarthritis of the knee: evidence-based guideline, 2nd edition.

Jevsevar DS. J Am Acad Orthop Surg. 2013;21(9):571-576.

2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee.

Kolasinski SL, et al. Arthritis Care Res (Hoboken). 2020;72(2):149-162.

Osteoarthritis: care and management in adults.

National Clinical Guideline Centre (UK). London: National Institute for Health and Care Excellence (UK); 2014

Patient Resources

American Chronic Pain Association

American College of Rheumatology

Centers for Disease Control and Prevention

Osteoarthritis Action Alliance

U.S. Pain Foundation

Clinical Assessment Tools

Hip Disability and Osteoarthritis Outcome Score (HOOS)

Knee Injury and Osteoarthritis Outcome Score (KOOS)

WOMAC Osteoarthritis Index

Suggested Readings

Safety of oral non-selective non-steroidal anti-inflammatory drugs in osteoarthritis: what does the literature say?

Cooper C, et al. Drugs Aging. 2019;36(Suppl 1):15-24.

The efficacy, tolerability, and joint safety of fasinumab in osteoarthritis pain: a phase iib/iii double-blind, placebo-controlled, randomized clinical trial.

Dakin P, et al. Arthritis Rheumatol. 2019;71(11):1824-1834.

Nerve growth factor and pain mechanisms.

Denk F, et al. Annu Rev Neurosci. 2017;40:307-325.

CDC guideline for prescribing opioids for chronic pain — United States, 2016.

Dowell D, et al. MMWR Recomm Rep. 2016;65(1):1-49.

Enhanced recovery protocols in total joint arthroplasty: a review of the literature and their implementation.

Galbraith AS, et al. Ir J Med Sci. 2018;187(1):97-109.

Gandhi R, et al. CMAJ. 2014;186(5):347‐355.

Surgical management of hip osteoarthritis.

Osteoarthritis.

Hunter DJ, Bierma-Zeinstra S. Lancet. 2019;393(10182):1745-1759.

Knee osteoarthritis: a review of management options.

Hussain SM, et al. Scott Med J. 2016;61(1):7‐16.

Efficacy and safety of oral NSAIDs and analgesics in the management of osteoarthritis: evidence from real-life setting trials and surveys.

Pelletier JP, et al. Semin Arthritis Rheum. 2016;45(suppl 4):S22-S27.

Effect of tanezumab on joint pain, physical function, and patient global assessment of osteoarthritis among patients with osteoarthritis of the hip or knee: a randomized clinical trial.

Schnitzer TJ, et al. JAMA. 2019;322(1):37-48.

Nonsurgical management of osteoarthritis knee pain in the older adult.

Taylor N. Clin Geriatr Med. 2017;33(1):41‐51.

Interactive Presentation

Osteoarthritis Pathophysiology and Novel Treatment Targets

Presented by Jeffrey Gudin, MD

Activity
Finding Relief in Osteoarthritis

New Paths to Chronic Pain Management

More information

Relevant Resources

Persistent and Breakthrough Pain

Balancing the Benefits and Risk of Opioid-Based Therapy

Improving the Care of Patients With Chronic Pain

Individualized Assessment and Mechanism-Based Multimodal Treatment

Caring For Patients With Chronic Pain

Responsible Opioid Prescribing to Achieve Individualized Functional Goals

Acute Management of Migraine Attacks

Overcoming Pain and Gastrointestinal Distress to Improve Patient Outcomes

Opioid-Induced Constipation

Proactive Diagnosis and Targeted Management

Intrathecal Drug Delivery for Chronic Pain

Selecting Patients and Optimizing Long-Term Outcomes

Clinical Updates on the Management of Gout

Evidence-Based Strategies for Improved Patient Outcomes

Opioid-Induced Constipation

Proactive Diagnosis and Targeted Management

Chronic Obstructive Pulmonary Disease, Asthma, or Both

Differential Diagnosis and Comprehensive Management Strategies

Improving Outcomes in Chronic Obstructive Pulmonary Disease

Optimizing Maintenance Therapy Across Healthcare Settings

Managing Gout in Primary Care

Evolving Strategies for Diagnosis and Long-Term Management

Clinical Issues in Chronic Pain

Consensus and Controversies for Responsible Opioid Prescribing

Noninsulin Approaches to Managing Type 2 Diabetes

Best Practices in Combination Therapy

Intrathecal Drug Delivery for Chronic Pain

The Role of Nurses in Optimizing Long-term Outcomes

Hitting the Target in Type 2 Diabetes

Evolving Approaches to Insulin Based Therapy

Intrathecal Drug Therapy for Chronic Pain

Evolving Best-Practice Strategies to Maximize Efficacy and Safety

Clearing the Air

Improving Outcomes for Patients with COPD

Clinical Updates in Type 2 Diabetes

New Strategies for Insulin Replacement Therapy

How Low Do You Go?

Clinical Updates in LDL-C Management

Incretin-Based Therapies For Type 2 Diabetes

Improving Comprehensive Patient Care

Improving Outcomes in Non–24-Hour Sleep-Wake Disorder

Identifying Patients and Tailoring Therapy

Comprehensive Management of Chronic Obstructive Pulmonary Disease

Collaborative Approaches to Guideline-Concordant Patient Care

Clinical Updates in the Management of Severe Asthma

New Strategies for Individualizing Long-term Care

Comprehensive Chronic Pain Management

A Focus on Patients With Opioid-Induced Constipation

Clinical Issues in Bipolar Depression

Consensus and Controversies Across the Spectrum of Patient Presentations

Clinical Updates in Rheumatoid Arthritis

Evolving Treatment Algorithms and Expert Perspectives on Biosimilars

Best Practices in Intrathecal Therapy for Chronic Pain

Patient Selection, Treatment Initiation, and Ongoing Monitoring

Overcoming Challenges in Cancer Pain Management

Engaging With Patients About Opioid-Induced Constipation

Caring for Patients with Severe Asthma

Evolving Best Practices to Optimize Outcomes

Can You Spot Axial Spondyloarthritis?

The PCP’s Role in Timely Recognition and Referral

Clinical Issues in Chronic Pain

Debates and Discussions About Therapeutically Targeting Nerve Growth Factor Signaling

Advancing the Care of Severe Asthma

Differential Diagnosis, Multidisciplinary Management, and Patient Engagement

Updates in HCV Screening and Treatment

Key Issues Impacting OB/GYN Practice

Comprehensive Relief from Cancer Pain

Expanding the Conversation on Opioid-Induced Constipation

Evolving Models of HIV Care

Volume II: Expanding Evidence for the Role of Rapid ART Initiation in HIV Practice

Managing Opioid-Induced Constipation

Translating Guidelines Into Patient Care

Clearing the Air in Severe Asthma Management

Improving Patient Outcomes Through Shared Clinical Decision Making

GLP-1 Receptors Agonists in Type 2 Diabetes

Mechanistic Insights and Evolving Treatment Options

Airing It Out

A Case-Based Conversation on Managing Asthma and Chronic Rhinosinusitis With Nasal Polyposis

COPD in Managed Care

The Clinical and Utilization Benefits of Exacerbation Prevention

Assimilating the Evidence in T2DM

Cardiovascular and Renal Outcomes With SGLT2 Inhibitors

Demystifying New Evidence for COPD Management

Best Practices for Primary Care

The Changing Landscape of HIV Prevention

What the Pharmacist Needs to Know about PrEP

What’s New in Systemic Lupus Erythematosus?

Unlocking Novel Paths to Patient Care

Expert Views on the Changing Landscape in RA

The Increasing Role of JAK Inhibitors

COPD Cases & Conversations

Preventing COPD Exacerbations to Improve Outcomes

Comprehensive Management in COPD

A Whole Patient Case Series

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SHOW COLUMNS FROM `interactions`
 1 0.001110 0.001110 0.001110 0.001110
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
 2 0.000981 0.000490 0.000474 0.000507
SHOW COLUMNS FROM `resource_videos`
 1 0.000951 0.000951 0.000951 0.000951
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
 2 0.000871 0.000435 0.000251 0.000620
SELECT `videos`.`id` AS `t1_c0`, `videos`.`vzaar_id` AS `t1_c1`, `videos`.`title` AS `t1_c2`, `videos`.`description` AS `t1_c3`, `videos`.`resource_id` AS `t1_c4`, `videos`.`type` AS `t1_c5` FROM `resource_videos` `videos` WHERE (`videos`.`resource_id`=:ypl0)
 1 0.000546 0.000546 0.000546 0.000546
SELECT * FROM `resources` `t` WHERE `t`.`id`=145 LIMIT 1
 1 0.000462 0.000462 0.000462 0.000462
SHOW CREATE TABLE `resources`
 1 0.000365 0.000365 0.000365 0.000365
SHOW CREATE TABLE `users`
 1 0.000330 0.000330 0.000330 0.000330
SHOW CREATE TABLE `resource_videos`
 1 0.000323 0.000323 0.000323 0.000323
SHOW CREATE TABLE `interactions`
 1 0.000296 0.000296 0.000296 0.000296
SHOW CREATE TABLE `activities`
 1 0.000292 0.000292 0.000292 0.000292
# Query Time (s)
0
select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
 0.001012
1
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
 0.000620
2
select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
 0.000277
3
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
 0.000251
4
SHOW COLUMNS FROM `resources`
 0.001423
5
SHOW CREATE TABLE `resources`
 0.000365
6
SELECT * FROM `resources` `t` WHERE `t`.`id`=145 LIMIT 1
 0.000462
7
SHOW COLUMNS FROM `interactions`
 0.001110
8
SHOW CREATE TABLE `interactions`
 0.000296
9
SHOW COLUMNS FROM `resource_videos`
 0.000951
10
SHOW CREATE TABLE `resource_videos`
 0.000323
11
SELECT `videos`.`id` AS `t1_c0`, `videos`.`vzaar_id` AS `t1_c1`, `videos`.`title` AS `t1_c2`, `videos`.`description` AS `t1_c3`, `videos`.`resource_id` AS `t1_c4`, `videos`.`type` AS `t1_c5` FROM `resource_videos` `videos` WHERE (`videos`.`resource_id`=:ypl0)
 0.000546
12
SHOW COLUMNS FROM `activities`
 0.001355
13
SHOW CREATE TABLE `activities`
 0.000292
14
SHOW COLUMNS FROM `users`
 0.001186
15
SHOW CREATE TABLE `users`
 0.000330
16
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
 0.000507
17
INSERT INTO `users` (`role`, `sendEmails`, `sendSms`, `source`, `session`, `lastLogin`, `phone`, `createDate`) VALUES (:yp0, :yp1, :yp2, :yp3, :yp4, :yp5, :yp6, :yp7)
 0.010167
18
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
 0.000474
19
UPDATE `users` SET `lastLogin`=:yp0 WHERE `users`.`id`=2540048
 0.002968
20
SELECT `activities`.`id` AS `t1_c0`, `activities`.`group_id` AS `t1_c1`, `activities`.`resource_id` AS `t1_c2`, `activities`.`title` AS `t1_c3`, `activities`.`type` AS `t1_c4`, `activities`.`facultyNames` AS `t1_c5`, `activities`.`shortDescription` AS `t1_c6`, `activities`.`fullDescription` AS `t1_c7`, `activities`.`creditAmount` AS `t1_c8`, `activities`.`shortAddress` AS `t1_c9`, `activities`.`creditType` AS `t1_c10`, `activities`.`startDate` AS `t1_c11`, `activities`.`finishDate` AS `t1_c12`, `activities`.`sponsors` AS `t1_c13`, `activities`.`status` AS `t1_c14`, `activities`.`createDate` AS `t1_c15`, `activities`.`image` AS `t1_c16`, `activities`.`image_featured` AS `t1_c17`, `activities`.`archived` AS `t1_c18`, `activities`.`managers_list` AS `t1_c19`, `activities`.`is_send_pp_email` AS `t1_c20`, `activities`.`muvi_sync_date` AS `t1_c21`, `activities`.`expert_questions` AS `t1_c22` FROM `activities` `activities` WHERE (`activities`.`resource_id`=:ypl0)
 0.001638
21
SELECT r.id, COUNT(r.id) relevance FROM resources r join `resource_topics` rtj on rtj.`resource_id`=r.id WHERE rtj.`topic_id` in (SELECT topic_id from `resource_topics` rt where rt.`resource_id`=:rid AND rt.topic_id>0) AND r.id <> :rid AND r.status = 'active' Group by r.id order by relevance DESC, r.`createDate` DESC
 0.003526
22
SELECT * FROM `resources` `t` WHERE `t`.`id` IN (149, 69, 55, 41, 40, 36, 31, 23, 178, 172, 164, 163, 154, 153, 147, 144, 143, 141, 140, 139, 137, 136, 132, 126, 122, 116, 114, 111, 107, 96, 94, 91, 90, 83, 62, 61, 59, 58, 56, 54, 53, 52, 51, 50, 48, 47, 44, 42, 39, 38, 34, 35, 32, 28, 26, 25, 21, 17, 12, 10, 7)
 0.005436
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