Image
Clinical Research Updates™

Clinical Updates in Rheumatoid Arthritis

New Perspectives on Targeting Remission and Individualizing Therapy

Clinical Practice Guidelines

2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis.

Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions.

Smolen JS, et al. Ann Rheum Dis. 2013;72(4):482-492.

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update.

Smolen JS, et al. Ann Rheum Dis. 2017;76(6):960-977.

Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force.

Smolen JS, et al. Ann Rheum Dis. 2016;75(1):3-15.

Patient Resources

American College of Rheumatology Disease Overview

The American College of Rheumatology has published a concise overview to help patients and caregivers learn more about rheumatoid arthritis and to provide tips for living well with this rheumatic disease.

American College of Rheumatology Patient Education Videos

The American College of Rheumatology has produced a library of videos about the impact of rheumatic disease, what to do when diagnosed with rheumatic disease, when to see a rheumatologist, and what patients have to say about their experiences of living with rheumatic disease.

Arthritis Foundation

The Arthritis Foundation provides self-care tools and resources covering treatment options, pain management, diet and exercise, and common comorbidities associated with many different arthritic conditions.

Handout on Health: Rheumatoid Arthritis

A publication from the National Institute of Arthritis and Musculoskeletal and Skin Diseases for people who have rheumatoid arthritis, as well as for their family members, friends, and others who want to find out more about this disease.

Rheumatoid Arthritis Support Network

The Rheumatoid Arthritis Support Network provides up-to-date information for patients with rheumatoid arthritis, including links to patient support groups, blogs written by patients with rheumatoid arthritis, resources to help pay for medications, and smart device apps to help track symptoms over time.

Suggested Readings

Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study.

McInnes IB, et al. Ann Rheum Dis. 2015;74(4):694-702.

Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, parallel-group phase III trial.

Burmester GR, et al. Ann Rheum Dis. 2017;76(5):840-847.

IL-6 inhibitors for treatment of rheumatoid arthritis: past, present, and future.

Kim GW, et al. Arch Pharm Res. 2015;38(5):575-584.

Measures of rheumatoid arthritis disease activity.

Anderson JK, et al. Arthritis Care Res (Hoboken). 2011;63(suppl 11):S14-S36.

The pathogenesis of rheumatoid arthritis.

McInnes IB, Schett G. N Engl J Med. 2011;365(23):2205-2219.

Rheumatoid arthritis disease activity measures: American College of Rheumatology recommendations for use in clinical practice.

Anderson J et al. Arthritis Care Res (Hoboken). 2012;64(5):640-647.

Sarilumab improves patient-reported outcomes in rheumatoid arthritis patients with inadequate response/intolerance to tumour necrosis factor inhibitors.

Strand V, et al. RMD Open. 2017;3(1):e000416.

Sarilumab plus methotrexate in patients with active rheumatoid arthritis and inadequate response to methotrexate: results of a phase III study.

Genovese MC, et al. Arthritis Rheumatol. 2015;67(6):1424-1437.

Sarilumab and nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis and inadequate response or intolerance to tumor necrosis factor inhibitors.

Fleischmann R, et al. Arthritis Rheumatol. 2017;69(2):277-290.

Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.

Dennis G Jr, et al. Arthritis Res Ther. 2014;16(2):R90.

Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial.

Burmester GR, et al. Ann Rheum Dis. 2016;75(6):1081-1091.

Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year.

Kremer JM, et al. Arthritis Rheum. 2011;63(3):609-621.

Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial

Gabay C, et al. Lancet. 2013;381(9877):1541-1550.

Activity
Clinical Updates in Rheumatoid Arthritis

New Perspectives on Targeting Remission and Individualizing Therapy

Relevant Resources

Clinical Updates in Systemic Lupus Erythematosus

Improved Diagnostic and Management Strategies

Advances in Immunosupressive Therapy for Solid Organ Transplantation

Long-Term Management Strategies to Improve Patient Outcomes

Clinical Updates on the Management of Gout

Evidence-Based Strategies for Improved Patient Outcomes

Managing Gout in Primary Care

Evolving Strategies for Diagnosis and Long-Term Management

Improving Outcomes in Rheumatoid Arthritis

Treating to Target, IL-6-Directed Therapies, and Evolving Management Algorithms

Clinical Updates in Rheumatoid Arthritis

Evolving Treatment Algorithms and Expert Perspectives on Biosimilars

Going Deeper on Atopic Dermatitis

Pathophysiology to the Management of Moderate-to-Severe Disease

Looking Beneath The Surface In Atopic Dermatitis

Targeting Immune Dysregulation and Delivering Comprehensive Care

Evolving Treatment Paradigms For Rheumatoid Arthritis

Translating Comprehensive Patient Evaluations Into Personalized Therapy

A Better Look at Rheumatoid Arthritis

Using Imaging to Improve Patient Outcomes

Clinical Issues in Rheumatoid Arthritis

Discussions and Debates on the Evolving Roles of Targeted Synthetic DMARDs

Pathways to Better Outcomes in Systemic Lupus Erythematosus

Translating Pathophysiology into Targeted Treatments

The Big Picture of IBD

An Interactive Experience Highlighting Recent Clinical Advances

Clinical Issues in Rheumatoid Arthritis

Debates & Discussions on the Evolving Role of JAK Inhibitors

Clinical Issues in Rheumatoid Arthritis

The Evolving Role of JAK Inhibitors

JAKi in RA Practice

Unpacking the Evidence for Their Use Today and Tomorrow

What’s New in Systemic Lupus Erythematosus?

Unlocking Novel Paths to Patient Care

Expert Views on the Changing Landscape in RA

The Increasing Role of JAK Inhibitors

Updates in Systemic Lupus Erythematosus

Unlocking Novel Paths to Patient Care

Swimming Upstream in Severe Asthma

New Pathways to Patient Management

Optimizing Advanced Therapies in Ulcerative Colitis: Is Your Practice Up to Date?

A Focus on Clinical Evidence and Guideline Recommendations

TOOLBAR

Yii 1.1.12

Request
Request Server Parameters
USER 'www-data'
HOME '/var/www'
HTTP_CONNECTION 'Keep-Alive'
HTTP_HOST 'www.exchangecme.com'
HTTP_ACCEPT_ENCODING 'br,gzip'
HTTP_IF_MODIFIED_SINCE 'Mon, 02 Aug 2021 18:33:10 GMT'
HTTP_ACCEPT_LANGUAGE 'en-US,en;q=0.5'
HTTP_ACCEPT 'text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8'
HTTP_USER_AGENT 'CCBot/2.0 (https://commoncrawl.org/faq/)'
PATH_INFO '/index.php'
REDIRECT_STATUS '200'
HTTPS 'on'
SERVER_NAME 'exchangecme.com'
SERVER_PORT '443'
SERVER_ADDR '172.31.18.208'
REMOTE_PORT '57070'
REMOTE_ADDR '3.236.232.99'
SERVER_SOFTWARE 'nginx/1.4.6'
GATEWAY_INTERFACE 'CGI/1.1'
SERVER_PROTOCOL 'HTTP/1.1'
DOCUMENT_ROOT '/var/www/exchangecme'
DOCUMENT_URI '/index.php'
REQUEST_URI '/RAroundtable'
SCRIPT_NAME '/index.php'
SCRIPT_FILENAME '/var/www/exchangecme/index.php'
CONTENT_LENGTH ''
CONTENT_TYPE ''
REQUEST_METHOD 'GET'
QUERY_STRING ''
FCGI_ROLE 'RESPONDER'
PHP_SELF '/index.php/index.php'
REQUEST_TIME_FLOAT 1634406163.1441
REQUEST_TIME 1634406163
Request Cookies
Session Attributes
Request GET Parameters
id '78'
Request POST Parameters
Request FILES
Application Settings
Application Properties
defaultController 'site'
layout 'main'
controllerMap array
(
'debug' => array
(
'class' => 'YiiDebugController'
)
)
catchAllRequest null
controllerNamespace null
name 'ExchangeCME'
charset 'UTF-8'
sourceLanguage 'en_us'
preload array
(
0 => 'log'
)
behaviors array()
Modules
gii array
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'class' => 'system.gii.GiiModule'
'password'
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'ipFilters'
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(
0 => '*'
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Application Params
dateFormat 'm/d/Y'
lastTimeToAttendEvent 172800
passTestLine 70
maxFileSize 1048576
imageDir '/var/www/exchangecme/files/upload/images'
linkImageDir '/files/upload/images'
linkInterDir '/files/upload/interactions'
actUpDir '/activities'
newsUpDir '/news'
resUpDir '/resources'
evUpDir '/events'
interScormDir '/scorm'
environment 'prod'
mandrillApiKey 'bOVWUkHldCbJevygSZtrVg'
rememberTime 'INTERVAL 1 DAY'
fromEmail 'support@exchangeCME.com'
fromName 'exchangeCME.com'
infoEmail 'info@exchangecme.com'
infoEmail2 'info@integritasgrp.com'
subject 'Registration'
certificates array
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2 => array
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'w' => 30
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sms array
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adobeConnect array
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timeZone 'America/New_York'
bigmarketWebinar array
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baseUrl 'https://www.exchangecme.com'
zoomWebinar array
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'access_token'
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urlManager array
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'groups/<group:[\w\d.-]+>'
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'group-events/<group:[\w\d.-]+>'
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'googleSearch'
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'subscription'
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'events'
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'resources'
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'<controller:(certificates|news|questions|site|users|activities|eventActivities|events)>/<action:\w+>'
=> '<controller>/<action>'
'<controller:(survey)>/<surveyId:\d+>/<email:[\w\d@.-]+>'
=> 'activities/survey'
0 => array
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'<id:[\w\d.-]+>/reportcenter/' => 'manager/viewReport'
'groups/<id:[\w\d.-]+>/reportcenter/'
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'manager/activities'
=> 'manager/viewActivities'
'manager/group-activities'
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)
'urlSuffix' => ''
'showScriptName'
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'appendParams' => true
'routeVar' => 'r'
'caseSensitive'
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'matchValue' => false
'cacheID' => 'cache'
'useStrictParsing'
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'urlRuleClass' => 'CUrlRule'
'behaviors'
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request array
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'csrfTokenName' => 'YII_CSRF_TOKEN'
'csrfCookie'
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'behaviors' => array()
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db array
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'class' => 'CDbConnection'
'connectionString'
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'username'
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'password'
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'schemaCachingDuration'
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'schemaCachingExclude' => array()
'schemaCacheID' => 'cache'
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'queryCacheID' => 'cache'
'autoConnect'
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'sqlite2'
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'mssql'
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'dblib'
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'sqlsrv'
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'oci'
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'pdoClass' => 'PDO'
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log array
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viewRenderer array
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clientScript array
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'yii' => array
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'yiitab' => array
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'depends' => array
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'depends' => array
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'bgiframe' => array
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0 => 'jquery'
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)
'ajaxqueue' => array
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'js' => array
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'depends' => array
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0 => 'jquery'
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'autocomplete' => array
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'js' => array
(
0 => 'jquery.autocomplete.js'
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'depends' => array
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0 => 'jquery'
1 => 'bgiframe'
2 => 'ajaxqueue'
)
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'maskedinput' => array
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'js' => array
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0 => 'jquery.maskedinput.min.js'
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'depends' => array
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'cookie' => array
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'js' => array
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'depends' => array
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'treeview' => array
(
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(
0 => 'jquery.treeview.js'
1 => 'jquery.treeview.edit.js'
2 => 'jquery.treeview.async.js'
)
'depends' => array
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0 => 'jquery'
1 => 'cookie'
)
)
'multifile' => array
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'depends' => array
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0 => 'jquery'
)
)
'rating' => array
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'js' => array
(
0 => 'jquery.rating.js'
)
'depends' => array
(
0 => 'jquery'
1 => 'metadata'
)
)
'metadata' => array
(
'js' => array
(
0 => 'jquery.metadata.js'
)
'depends' => array
(
0 => 'jquery'
)
)
'bbq' => array
(
'js' => array
(
0 => 'jquery.ba-bbq.js'
)
'depends' => array
(
0 => 'jquery'
)
)
'history' => array
(
'js' => array
(
0 => 'jquery.history.js'
)
'depends' => array
(
0 => 'jquery'
)
)
)
'scripts' => array()
'coreScriptPosition' => 0
'defaultScriptFilePosition' => 0
'defaultScriptPosition' => 4
'behaviors' => array()
)
assetManager array
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'linkAssets'
=> false
'excludeFiles' => array
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0 => '.svn'
1 => '.gitignore'
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'newFileMode' => 438
'newDirMode' => 511
'forceCopy' => false
'behaviors' => array()
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themeManager array
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'themeClass'
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'behaviors'
=> array()
)
session array
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'class' => 'CHttpSession'
'autoStart'
=> true
'behaviors' => array()
)
user array
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'allowAutoLogin'
=> true
'guestName' => 'Guest'
'loginUrl'
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(
0 => '/users/personalization'
)
'identityCookie' => null
'authTimeout' => null
'autoRenewCookie' => false
'autoUpdateFlash' => true
'loginRequiredAjaxResponse' => null
'behaviors' => array
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(
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)
)
widgetFactory array
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'enableSkin'
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'widgets' => array()
'skinnableWidgets' => null
'skinPath' => null
'behaviors' => array()
)
messages array
(
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'cachingDuration'
=> 0
'cacheID' => 'cache'
'basePath'
=> '/var/www/exchangecme/protected/messages'
'forceTranslation'
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'behaviors' => array()
)
Views Rendering
Context ResourcesController
Context class ResourcesController
Inheritance Controller » CController » CBaseController
Defined in file protected/controllers/ResourcesController.php
Context properties
  •  => 
  •  => 
  •  => 
  •  => 
  •  => 
Route resources/view
Action CInlineAction (view)
Action params
  •  => 
Render methodrenderPartial
View file themes/desktop/views/resources/view.php
View data
  •  => 
Context ResourcesController
Context class ResourcesController
Inheritance Controller » CController » CBaseController
Defined in file protected/controllers/ResourcesController.php
Context properties
  •  => 
  •  => 
  •  => 
  •  => 
  •  => 
Route resources/view
Action CInlineAction (view)
Action params
  •  => 
Render methodrenderPartial
View file themes/desktop/views/resources/_activity.php
View data
  •  => 
Context ResourcesController
Context class ResourcesController
Inheritance Controller » CController » CBaseController
Defined in file protected/controllers/ResourcesController.php
Context properties
  •  => 
  •  => 
  •  => 
  •  => 
  •  => 
Route resources/view
Action CInlineAction (view)
Action params
  •  => 
Render methodrender
View file protected/views/layouts/column1.php
Context ResourcesController
Context class ResourcesController
Inheritance Controller » CController » CBaseController
Defined in file protected/controllers/ResourcesController.php
Context properties
  •  => 
  •  => 
  •  => 
  •  => 
  •  => 
Route resources/view
Action CInlineAction (view)
Action params
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Render methodrender
View file themes/desktop/views/layouts/main.php
Context ResourcesController
Context class ResourcesController
Inheritance Controller » CController » CBaseController
Defined in file protected/controllers/ResourcesController.php
Context properties
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  •  => 
  •  => 
  •  => 
Route resources/view
Action CInlineAction (view)
Action params
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Render methodrenderPartial
View file themes/desktop/views/common/_footer.php
View data
    null
Context ResourcesController
Context class ResourcesController
Inheritance Controller » CController » CBaseController
Defined in file protected/controllers/ResourcesController.php
Context properties
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  •  => 
  •  => 
  •  => 
Route resources/view
Action CInlineAction (view)
Action params
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Render methodrenderPartial
View file themes/desktop/views/common/elasticsearch.php
View data
    null
Context YiiDebugToolbarResourceUsage
Context class YiiDebugToolbarResourceUsage
Inheritance CWidget » CBaseController
Defined in file protected/extensions/malyshev/yii-debug-toolbar/widgets/YiiDebugToolbarResourceUsage.php
Context properties
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  •  => 
  •  => 
Render methodrender
View file protected/extensions/malyshev/yii-debug-toolbar/widgets/views/resources.php
View data
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SQL Queries from 1 connection (21/0.023332s)

Connection ID: db (CDbConnection)

Driver mysql
Server Version 5.5.59-0ubuntu0.14.04.1
Uptime 17w 4d 0h 42m 7s
Threads 1
Questions 48187235
Slow queries 17
Opens 210
Flush tables 1
Open tables 176
Queries per second avg 4.533
Query Count Total (s) Avg. (s) Min. (s) Max. (s)
INSERT INTO `users` (`role`, `sendEmails`, `sendSms`, `source`, `session`, `lastLogin`, `phone`, `createDate`) VALUES (:yp0, :yp1, :yp2, :yp3, :yp4, :yp5, :yp6, :yp7)
1 0.003711 0.003711 0.003711 0.003711
SELECT r.id, COUNT(r.id) relevance FROM resources r join `resource_topics` rtj on rtj.`resource_id`=r.id WHERE rtj.`topic_id` in (SELECT topic_id from `resource_topics` rt where rt.`resource_id`=:rid AND rt.topic_id>0) AND r.id <> :rid AND r.status = 'active' Group by r.id order by relevance DESC, r.`createDate` DESC
1 0.003383 0.003383 0.003383 0.003383
UPDATE `users` SET `lastLogin`=:yp0 WHERE `users`.`id`=2539835
1 0.002886 0.002886 0.002886 0.002886
SELECT `activities`.`id` AS `t1_c0`, `activities`.`group_id` AS `t1_c1`, `activities`.`resource_id` AS `t1_c2`, `activities`.`title` AS `t1_c3`, `activities`.`type` AS `t1_c4`, `activities`.`facultyNames` AS `t1_c5`, `activities`.`shortDescription` AS `t1_c6`, `activities`.`fullDescription` AS `t1_c7`, `activities`.`creditAmount` AS `t1_c8`, `activities`.`shortAddress` AS `t1_c9`, `activities`.`creditType` AS `t1_c10`, `activities`.`startDate` AS `t1_c11`, `activities`.`finishDate` AS `t1_c12`, `activities`.`sponsors` AS `t1_c13`, `activities`.`status` AS `t1_c14`, `activities`.`createDate` AS `t1_c15`, `activities`.`image` AS `t1_c16`, `activities`.`image_featured` AS `t1_c17`, `activities`.`archived` AS `t1_c18`, `activities`.`managers_list` AS `t1_c19`, `activities`.`is_send_pp_email` AS `t1_c20`, `activities`.`muvi_sync_date` AS `t1_c21`, `activities`.`expert_questions` AS `t1_c22` FROM `activities` `activities` WHERE (`activities`.`resource_id`=:ypl0)
1 0.001678 0.001678 0.001678 0.001678
SELECT * FROM `resources` `t` WHERE `t`.`id` IN (170, 169, 167, 164, 153, 149, 131, 127, 110, 98, 97, 95, 86, 82, 77, 75, 67, 60, 58, 46, 35, 28, 22, 5)
1 0.001526 0.001526 0.001526 0.001526
SHOW COLUMNS FROM `resources`
1 0.001390 0.001390 0.001390 0.001390
SHOW COLUMNS FROM `activities`
1 0.001271 0.001271 0.001271 0.001271
SHOW COLUMNS FROM `users`
1 0.001213 0.001213 0.001213 0.001213
select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
2 0.001127 0.000564 0.000276 0.000851
SHOW COLUMNS FROM `resource_videos`
1 0.001007 0.001007 0.001007 0.001007
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
2 0.000933 0.000467 0.000318 0.000615
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
2 0.000912 0.000456 0.000452 0.000460
SELECT `videos`.`id` AS `t1_c0`, `videos`.`vzaar_id` AS `t1_c1`, `videos`.`title` AS `t1_c2`, `videos`.`description` AS `t1_c3`, `videos`.`resource_id` AS `t1_c4`, `videos`.`type` AS `t1_c5` FROM `resource_videos` `videos` WHERE (`videos`.`resource_id`=:ypl0)
1 0.000548 0.000548 0.000548 0.000548
SELECT * FROM `resources` `t` WHERE `t`.`id`=78 LIMIT 1
1 0.000477 0.000477 0.000477 0.000477
SHOW CREATE TABLE `resources`
1 0.000338 0.000338 0.000338 0.000338
SHOW CREATE TABLE `activities`
1 0.000318 0.000318 0.000318 0.000318
SHOW CREATE TABLE `users`
1 0.000312 0.000312 0.000312 0.000312
SHOW CREATE TABLE `resource_videos`
1 0.000302 0.000302 0.000302 0.000302
# Query Time (s)
0
select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
0.000851
1
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
0.000615
2
select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
0.000276
3
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
0.000318
4
SHOW COLUMNS FROM `resources`
0.001390
5
SHOW CREATE TABLE `resources`
0.000338
6
SELECT * FROM `resources` `t` WHERE `t`.`id`=78 LIMIT 1
0.000477
7
SHOW COLUMNS FROM `resource_videos`
0.001007
8
SHOW CREATE TABLE `resource_videos`
0.000302
9
SELECT `videos`.`id` AS `t1_c0`, `videos`.`vzaar_id` AS `t1_c1`, `videos`.`title` AS `t1_c2`, `videos`.`description` AS `t1_c3`, `videos`.`resource_id` AS `t1_c4`, `videos`.`type` AS `t1_c5` FROM `resource_videos` `videos` WHERE (`videos`.`resource_id`=:ypl0)
0.000548
10
SHOW COLUMNS FROM `activities`
0.001271
11
SHOW CREATE TABLE `activities`
0.000318
12
SHOW COLUMNS FROM `users`
0.001213
13
SHOW CREATE TABLE `users`
0.000312
14
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
0.000460
15
INSERT INTO `users` (`role`, `sendEmails`, `sendSms`, `source`, `session`, `lastLogin`, `phone`, `createDate`) VALUES (:yp0, :yp1, :yp2, :yp3, :yp4, :yp5, :yp6, :yp7)
0.003711
16
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
0.000452
17
UPDATE `users` SET `lastLogin`=:yp0 WHERE `users`.`id`=2539835
0.002886
18
SELECT `activities`.`id` AS `t1_c0`, `activities`.`group_id` AS `t1_c1`, `activities`.`resource_id` AS `t1_c2`, `activities`.`title` AS `t1_c3`, `activities`.`type` AS `t1_c4`, `activities`.`facultyNames` AS `t1_c5`, `activities`.`shortDescription` AS `t1_c6`, `activities`.`fullDescription` AS `t1_c7`, `activities`.`creditAmount` AS `t1_c8`, `activities`.`shortAddress` AS `t1_c9`, `activities`.`creditType` AS `t1_c10`, `activities`.`startDate` AS `t1_c11`, `activities`.`finishDate` AS `t1_c12`, `activities`.`sponsors` AS `t1_c13`, `activities`.`status` AS `t1_c14`, `activities`.`createDate` AS `t1_c15`, `activities`.`image` AS `t1_c16`, `activities`.`image_featured` AS `t1_c17`, `activities`.`archived` AS `t1_c18`, `activities`.`managers_list` AS `t1_c19`, `activities`.`is_send_pp_email` AS `t1_c20`, `activities`.`muvi_sync_date` AS `t1_c21`, `activities`.`expert_questions` AS `t1_c22` FROM `activities` `activities` WHERE (`activities`.`resource_id`=:ypl0)
0.001678
19
SELECT r.id, COUNT(r.id) relevance FROM resources r join `resource_topics` rtj on rtj.`resource_id`=r.id WHERE rtj.`topic_id` in (SELECT topic_id from `resource_topics` rt where rt.`resource_id`=:rid AND rt.topic_id>0) AND r.id <> :rid AND r.status = 'active' Group by r.id order by relevance DESC, r.`createDate` DESC
0.003383
20
SELECT * FROM `resources` `t` WHERE `t`.`id` IN (170, 169, 167, 164, 153, 149, 131, 127, 110, 98, 97, 95, 86, 82, 77, 75, 67, 60, 58, 46, 35, 28, 22, 5)
0.001526
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