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Symposium

Individualizing Antiplatelet Therapy for Acute Coronary Syndrome

Meeting Slides

Suggested Readings

Antman EM, Cohen M, Bernink PJ, et al. The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making. JAMA. 2000;284:835-842.

Jneid H, Anderson JL, Wright RS, et al. 2012 ACCF/AHA focused update of the guideline for the management of patients with unstable angina/non-ST-elevation myocardial infarction (updating the 2007 guideline and replacing the 2011 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2012;60:645-681.

Mehta SR, Tanguay JF, Eikelboom JW, et al. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet. 2010;376:1233-1243.

O’Gara PT, Kushner FG, Ascheim DD, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127:529-555.

Roe MT, Armstrong PW, Fox KA, et al. Prasugrel versus clopidogrel for acute coronary syndromes without revascularization. N Engl J Med. 2012;367:1297-1309.

Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2009;361:1045-1057.

Wiviott SD, E. Braunwald E, McCabe CH, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357:2001-2015.

Wiviott SD, White HD, Ohman EM, et al. Prasugrel versus clopidogrel for patients with unstable angina or non-ST-segment elevation myocardial infarction with or without angiography: a secondary, prespecified analysis of the TRILOGY ACS trial. Lancet. 2013;382:605-613.

Relevant Resources

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Query Count Total (s) Avg. (s) Min. (s) Max. (s)
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select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
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SHOW CREATE TABLE `resources`
1 0.004304 0.004304 0.004304 0.004304
SHOW CREATE TABLE `activities`
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1 0.001523 0.001523 0.001523 0.001523
SHOW COLUMNS FROM `resources`
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SHOW COLUMNS FROM `activities`
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SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
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SHOW COLUMNS FROM `resource_videos`
1 0.000924 0.000924 0.000924 0.000924
SELECT `videos`.`id` AS `t1_c0`, `videos`.`vzaar_id` AS `t1_c1`, `videos`.`title` AS `t1_c2`, `videos`.`description` AS `t1_c3`, `videos`.`resource_id` AS `t1_c4`, `videos`.`type` AS `t1_c5` FROM `resource_videos` `videos` WHERE (`videos`.`resource_id`=:ypl0)
1 0.000387 0.000387 0.000387 0.000387
SHOW CREATE TABLE `users`
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# Query Time (s)
0
select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
0.004646
1
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
0.000696
2
select id, status from activities where FIND_IN_SET(:shortAddress, shortAddress)
0.000335
3
select id from resources where FIND_IN_SET(:shortAddress, shortAddress)
0.004303
4
SHOW COLUMNS FROM `resources`
0.001490
5
SHOW CREATE TABLE `resources`
0.004304
6
SELECT * FROM `resources` `t` WHERE `t`.`id`=9 LIMIT 1
0.004641
7
SHOW COLUMNS FROM `interactions`
0.001091
8
SHOW CREATE TABLE `interactions`
0.000209
9
SHOW COLUMNS FROM `resource_videos`
0.000924
10
SHOW CREATE TABLE `resource_videos`
0.000202
11
SELECT `videos`.`id` AS `t1_c0`, `videos`.`vzaar_id` AS `t1_c1`, `videos`.`title` AS `t1_c2`, `videos`.`description` AS `t1_c3`, `videos`.`resource_id` AS `t1_c4`, `videos`.`type` AS `t1_c5` FROM `resource_videos` `videos` WHERE (`videos`.`resource_id`=:ypl0)
0.000387
12
SHOW COLUMNS FROM `activities`
0.001443
13
SHOW CREATE TABLE `activities`
0.004285
14
SHOW COLUMNS FROM `users`
0.001262
15
SHOW CREATE TABLE `users`
0.000383
16
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
0.000472
17
INSERT INTO `users` (`role`, `sendEmails`, `sendSms`, `source`, `session`, `lastLogin`, `phone`, `createDate`) VALUES (:yp0, :yp1, :yp2, :yp3, :yp4, :yp5, :yp6, :yp7)
0.014068
18
SELECT * FROM `users` `t` WHERE session=:session LIMIT 1
0.000516
19
UPDATE `users` SET `lastLogin`=:yp0 WHERE `users`.`id`=2491908
0.010202
20
SELECT `activities`.`id` AS `t1_c0`, `activities`.`group_id` AS `t1_c1`, `activities`.`resource_id` AS `t1_c2`, `activities`.`title` AS `t1_c3`, `activities`.`type` AS `t1_c4`, `activities`.`facultyNames` AS `t1_c5`, `activities`.`shortDescription` AS `t1_c6`, `activities`.`fullDescription` AS `t1_c7`, `activities`.`creditAmount` AS `t1_c8`, `activities`.`shortAddress` AS `t1_c9`, `activities`.`creditType` AS `t1_c10`, `activities`.`startDate` AS `t1_c11`, `activities`.`finishDate` AS `t1_c12`, `activities`.`sponsors` AS `t1_c13`, `activities`.`status` AS `t1_c14`, `activities`.`createDate` AS `t1_c15`, `activities`.`image` AS `t1_c16`, `activities`.`image_featured` AS `t1_c17`, `activities`.`archived` AS `t1_c18`, `activities`.`managers_list` AS `t1_c19`, `activities`.`is_send_pp_email` AS `t1_c20`, `activities`.`muvi_sync_date` AS `t1_c21`, `activities`.`expert_questions` AS `t1_c22` FROM `activities` `activities` WHERE (`activities`.`resource_id`=:ypl0)
0.005432
21
SELECT r.id, COUNT(r.id) relevance FROM resources r join `resource_topics` rtj on rtj.`resource_id`=r.id WHERE rtj.`topic_id` in (SELECT topic_id from `resource_topics` rt where rt.`resource_id`=:rid AND rt.topic_id>0) AND r.id <> :rid AND r.status = 'active' Group by r.id order by relevance DESC, r.`createDate` DESC
0.003205
22
SELECT * FROM `resources` `t` WHERE `t`.`id` IN (143, 132, 129, 122, 118, 109, 89, 81, 73, 51, 50, 49, 48, 45, 42, 38, 33, 30, 29, 20, 18, 16, 14, 13, 11, 4)
0.001523
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