Meeting slides
Interactive presentation

Scientific Insights Into the Kidneys and Glucose Homeostasis

Daniel Einhorn, MD, FACE, FACP
Suggested Readings

Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial

Bailey CJ, et al. Lancet. 2010;375(9733):2223-2233.

Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis

Baker WL, et al. J Am Soc Hypertens. 2014;8(4):262-275.

Sodium glucose co-transport 2 inhibitors in the treatment of type 2 diabetes mellitus: a meta-analysis of randomized double-blind controlled trials

Berhan A, Barker A. BMC Endocr Disord. 2013;13(1):58.

The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia

DeFronzo RA, et al. Diabetes Obes Metab. 2012;14(1):5-14.

Sodium–glucose linked transporter-2 inhibitors: potential for renoprotection beyond blood glucose lowering?

Gilbert RE. Kidney Int. 2013 Nov 20. [Epub ahead of print]

Management of hyperglycemia in type 2 diabetes: a patient-centered approach: Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Inzucchi SE, et al. Diabetes Care. 2012;35(6):1364-1379.

Clinical potential of sodium-glucose cotransporter 2 inhibitors in the management of type 2 diabetes

Kim Y, Babu AR. Diabetes Metab Syndr Obes. 2012;5:313-327.

SGLT-2 inhibitors and their potential in the treatment of diabetes

Rosenwasser RF, et al. Diabetes Metab Syndr Obes. 2013;6:453-467.

Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise

Stenlöf K, et al. Diabetes Obes Metab. 2013;15(4):372-382.

Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years

Wilding JPH, et al. Diabetes Obes Metab. 2014;16(2)124-136.

Linked Resources

Meeting Materials

Download slides presented at the ADA's 74th Scientific Session.


American Diabetes Association’s Standards of Medical Care in Diabetes—2014

The ADA’s Standards of Care provide clinicians, patients, researchers, payers, and other interested individuals with the components of good diabetes management, general treatment goals, and tools to evaluate the quality of care. Importantly, these recommendations should be adjusted based on individual preferences, comorbidities, and other patient-related factors.
American Diabetes Association. Diabetes Care. 2014;37(suppl 1):S14-S80.

American Association of Clinical Endocrinologists’ Comprehensive Diabetes Management Algorithm 2013

This algorithm from the AACE addresses evaluating the whole patient, potential risks and complications, and evidence-based treatment approaches for diabetes. The document contains sections on obesity, prediabetes, hyperglycemia therapy (lifestyle modifications, pharmacotherapy, and insulin), hypertension management, hyperlipidemia treatment, and other risk-reduction strategies.
Garber AJ, et al. Endocr Pract. 2013;19(suppl 1):1-48.

Kidney Disease Outcomes Quality Initiative Clinical Practice Guideline for Diabetes and Chronic Kidney Disease: 2012 Update

The 2012 update of the KDOQI Clinical Practice Guideline from the National Kidney Foundation can assist practitioners when caring for patients with diabetes who are at risk for or suffering from chronic kidney disease. This publication addresses appropriate hemoglobin A1c targets, lipid goals, and the use of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with diabetes with and without albuminuria.
National Kidney Foundation. Am J Kidney Dis. 2012;60(5):850-886.


Diabetes HealthSense

Provides easy access to resources to help you live well and meet your goals—whether you have diabetes or are at risk for the disease.

7 Self-Care Behaviors Monitoring Form from the American Association of Diabetes Educators

The AADE developed the 7 Self-Care Behaviors Monitoring Form to provide a structure for tracking diet, physical activity, medication adherence, and overall lifestyle modifications.

Diabetes Health Sense Web site from the National Diabetes Education Program

The NDEP has collected and posted resources for patients living with T2DM online at the Diabetes Health Sense Web site. In addition to recommendations on lifestyle changes and medication use, patients will find a blood sugar and daily activity log that supports dietary improvements, increased physical activity, and other lifestyle changes.

Diabetes 24/7 Online Monitoring Tool from the American Diabetes Association

Diabetes 24/7 is a helpful online tool for monitoring and documenting blood sugar levels. Patient reporting promotes diabetes self-management and data can be shared with health care providers.

Related activities
1.00 AMA PRA

The Kidneys in Type 2 Diabetes

Disturbed Glucose Homeostasis to Mechanism-Based Therapy

Faculty: Lawrence Blonde, MD, FACP, FACE; Daniel Einhorn, MD, FACE, FACP; Richard E. Pratley, MD
Release: 09/17/2014
Expiration: 09/17/2015