Clinical Issues in Bipolar DepressionConsensus and Controversies Across the Spectrum of Patient Presentations
Major depressive disorder and bipolar disorder predispose youth to accelerated atherosclerosis and early cardiovascular disease: a scientific statement from the American Heart Association.
Goldstein BI, et al. Circulation. 2015;132(10):965-986. 2015;8(4):206-220
Mixed specifier for bipolar mania and depression: highlights of DSM-5 changes and implications for diagnosis and treatment in primary care.
Hu J, et al. Prim Care Companion CNS Disord. 2014;16(2).
The prevalence and illness characteristics of DSM-5-defined “mixed feature specifier” in adults with major depressive disorder and bipolar disorder: Results from the International Mood Disorders Collaborative Project.
McIntyre RS, et al. J Affect Disord. 2015;172:259-264.
Lurasidone in the treatment of bipolar depression with mixed (subsyndromal hypomanic) features: post hoc analysis of a randomized placebo-controlled trial.
McIntyre RS, et al. J Clin Psychiatry. 2015;76(4):398-405.
Mixed depression in bipolar disorder: prevalence rate and clinical correlates during naturalistic follow-up in the Stanley Bipolar Network.
Miller S, et al. Am J Psychiatry. 2016; Apr 15. [Epub ahead of print].
A 6 week randomized double-blind placebo-controlled trial of ziprasidone for the acute depressive mixed state.
Patkar A, et al. PLoS One. 2012;7(4):e34757.
Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
Perlis RH, et al. Am J Psychiatry. 2006;163(2):217-224.0
Perugi G, et al. J Clin Psychiatry. 2015;76(3):e351-e358.
Factors related to suicidal behavior in patients with bipolar disorder: the effect of mixed features on suicidality.
Seo HJ, et al. Gen Hosp Psychiatry. 2016;39:91-96.
Tohen M, et al. J Affect Disord. 2014;164:57-62.
Zimmermann P, et al. Arch Gen Psychiatry. 2009;66(12):1341-1352.
Improved Diagnostic and Management Strategies
Overcoming Diagnostic Challenges, Targeting Remission, and Optimizing Cardiometabolic Health
New Approaches to Optimizing Patient Outcomes
Overcoming Diagnostic Barriers and Optimizing Long-Term Patient Outcomes
Overcoming Pain and Gastrointestinal Distress to Improve Patient Outcomes
Accelerating Diagnosis, Achieving Remission, and Encouraging Adherence
Evidence-Based Strategies for Improved Patient Outcomes
Proactive Diagnosis and Targeted Management
Differential Diagnosis and Comprehensive Management Strategies
Optimizing Maintenance Therapy Across Healthcare Settings
Evolving Strategies for Diagnosis and Long-Term Management
Consensus and Controversies for Responsible Opioid Prescribing
Managing Patients Across the Disease Spectrum
Best Practices in Combination Therapy
Evolving Approaches to Insulin Based Therapy
Best Practices for Emergency Care
Improving Outcomes for Patients with COPD
New Strategies for Insulin Replacement Therapy
Clinical Updates in LDL-C Management
Improving Comprehensive Patient Care
Identifying Patients and Tailoring Therapy
Collaborative Approaches to Guideline-Concordant Patient Care
New Strategies for Individualizing Long-term Care
A Focus on Patients With Opioid-Induced Constipation
Evolving Treatment Algorithms and Expert Perspectives on Biosimilars
Evolving Best Practices to Optimize Outcomes
The PCP’s Role in Timely Recognition and Referral
Differential Diagnosis, Multidisciplinary Management, and Patient Engagement
Key Issues Impacting OB/GYN Practice
Volume II: Expanding Evidence for the Role of Rapid ART Initiation in HIV Practice
Improving Patient Outcomes Through Shared Clinical Decision Making
Mechanistic Insights and Evolving Treatment Options
Clinical Resource Center