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Program Overview

With recent approvals of antiamyloid monoclonal antibodies (mAbs), the field of AD is rapidly changing. Implementation of these therapies requires new protocols and workflows in clinics, including collaboration among multiple departments. This grassroots initiative consists of a 2-part series of live, on-site meetings targeted toward neurology clinicians, radiology clinicians, emergency department staff, and infusion center staff. Drs. Lawrence Honig and David Weisman will discuss details of antiamyloid mAbs, collaboration and communication tips, and best practices for developing implementation protocols. They will also help troubleshoot each location’s protocol development. Participating locations will receive numerous handouts and checklists that will aid in development and implementation of these novel protocols and new workflow procedures.

Workshop 1 Agenda

Laying the Foundation for Administering Antiamyloid mAbs for Patients With Early AD

  • An introduction to antiamyloid mAbs
       - A review of FDA-approved antiamyloid mAbs
       - Patient selection criteria for antiamyloid mAbs
          * Proving early AD diagnosis: CSF and PET scans
          * CMS registry requirements
  • Preparing to manage adverse events
       - Understanding ARIA: occurrence, risks, and types
          * APOE4 genetic testing
          * Routine MRI monitoring and key identifiers for radiology
          * Adjusting dosages or stopping medication due toARIA
          * Could it be ARIA: lessons for emergency department clinicians and infusion center staff
       - Infusion site reactions: what infusion center staff need to know
  • Overview of staffing and workflow requirements to administer antiamyloid mAbs
  • Q&A: group discussion about individual practice needs and challenges to initial steps in clinic protocol development (this discussion will help form the content for Workshop #2)

Workshop 2 Agenda

(scheduled approximately 1 month after Workshop #1)

Overcoming Hurdles to Antiamyloid mAb Clinic Protocol Development

  • Coordinating care teams
       - Individual roles of the multidisciplinary care team members
       - Improving communication and role of EMR
       - Patient and caregiver education
          * Who is responsible for delivering education?
          * Establishing communication pathways with clinicians
  • Establishing protocol checklists: before, during, and after infusion
  • Exploring financial aspects of antiamyloid mAbs
  • Q&A and individualized troubleshooting: discussion may include site-specific challenges regarding interdepartmental communication, protocol checklists, scheduling or administrative barriers, or strategies for communicating with key decision-makers

This activity is provided by Integritas Communications.

This activity is supported by an educational grant from Eisai Inc.

events
JUL
18
2025
BRIDGE AD 2025
1.00 CME

Neurology Center of New England, PC

Time: 8:00 AM-9:00 AM ET
Venue: Neurology Center of New England, PC
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