A Day in the Life of a PrEP Provider: Decisions, Dilemmas, and Advances in Daily Practice

Preexposure prophylaxis (PrEP) continues to evolve as a cornerstone of HIV prevention, offering new opportunities to individualize care through oral and long-acting injectable (LAI) options. Because patient needs, preferences, and clinical circumstances vary, clinicians must be prepared to initiate nonstigmatizing sexual health conversations, select appropriate PrEP regimens, and apply current guideline recommendations for HIV testing, monitoring, and follow-up. Many providers, however, continue to face practical challenges related to regimen switching, missed injections, regimen persistence, workflow implementation, access, and care coordination in real-world practice. Led by HIV prevention expert Dr. Jason Halperin, this interactive “A Day in the Life” CME activity places learners inside a simulated PrEP clinic day, following a clinician through patient visits, peer consults, training sessions, and team-based discussions. Through immersive case scenarios and faculty-guided clinical insights, learners will explore evidence-based strategies for delivering patient-centered PrEP care across diverse populations.

Overall Learning Objectives

1. Initiate sexual health conversations in a nonstigmatizing manner
2. Describe guideline-directed HIV testing requirements for PrEP treatment initiation
3. Choose PrEP regimens based on clinical evidence, guidelines, and patient characteristics and preferences
4. Identify guideline recommendations for PrEP initiation, monitoring, and follow-up care
5. Devise workflow strategies for LAI PrEP implementation
6. Utilize established guidelines and recommendations to manage switching to different PrEP regimens

Target Audience

This series is designed to educate sexual health, infectious disease, and HIV specialists, as well as other current PrEP-prescribing primary care and internal medicine clinicians.