HIV Experts & Evidence™
A Two-Part Continuing Medical Education Series on the Evolving Models of HIV Care
This two-part activity is intended for infectious diseases and human immunodeficiency virus (HIV)-specialist physicians and other clinicians and stakeholders involved in the care of patients with HIV infection.
Guideline-based rapid initiation of antiretroviral therapy (ART) for treatment of HIV is now the standard of care.1 Best-practice rapid ART protocols promote immediate linkage to HIV care, decreased time to ART initiation, decreased time to viral suppression (VS), and long-term VS — even within vulnerable populations.2 Shorter time to VS is associated with decreases in the incidence of both AIDS- and non-AIDS–related events3 It further benefits the individual’s partners and at-risk populations by decreasing the period of time during which the virus is transmittable. This informs the Undetectable Equals Untransmittable (U=U) initiative, which serves not only the public health goal of ending the HIV/AIDS pandemic, but also brings equity to HIV care for vulnerable populations.4 Geared to the needs of HIV-specialist clinicians, this two-part HIV Experts and Evidence™ enduring activity will address rapid ART guidelines, provide practical solutions to systemic and clinical barriers that can impede access to rapid ART regimens and retention in care, and real-world approaches to enhanced patient-centered services.
1. U.S. Department of Health and Human Services. Guidelines for Use of Antiretroviral Agents in HIV-1−Infected Adults and Adolescents Living with HIV. Last updated July 2020. https://aidsinfo.nih.gov/guidelines. Accessed August 24, 2020.
2. Coffey S, et al. RAPID antiretroviral therapy: high virologic suppression rates with immediate ART initiation in a vulnerable urban clinic population AIDS. 2019;33(5):825-832.
3. The INSIGHT START Study Group. Initiation of antiretroviral therapy in early asymptomatic HIV infection. N Engl J Med. 2015;373(9):795-807.
4. Eisinger RW, et al. HIV viral load and transmissibility of HIV infection: undetectable equals untransmittable. JAMA. 2019;321(5):451-452.
After completing this activity, the participant should be better able to:
- Reduce time from HIV diagnosis to viral suppression to improve patient outcomes and prevent HIV transmission
- Select appropriate regimens for rapid ART initiation based on current guidelines and patient characteristics
- Implement strategies designed to decrease barriers to the provision of rapid ART to patients with newly diagnosed HIV infection
Jonathan A. Colasanti, MD, MSPH
Associate Professor of Medicine
Emory University School of Medicine
Medical Director, Infectious Diseases Program
Grady Health System
Jason Halperin, MD, MPH
Assistant Professor of Medicine
Tulane University School of Medicine
New Orleans, Louisiana
We would like to thank the American Academy of HIV Medicine (AAHIVM) for their collaboration and support.
This two-part activity is jointly provided by Global Education Group and Integritas Communications.
This two-part activity is supported by an independent educational grant from Gilead Sciences, Inc.
Evolving Models of HIV Care (Volume 3)