Immunocompromised Patients and COVID-19 Risks Activity 2

Jonathan Li, MD, MMSc & Lewis Teperman, MD, FACS

This activity is jointly provided by Global Education Group and Integritas Communications.


This educational activity is supported by an educational grant from AstraZeneca.


Jonathan Li, MD, MMSc
Associate Professor of Medicine
Brigham and Women’s Hospital
Harvard Medical School
Director, Harvard/Brigham Virology Specialty Laboratory
Boston, Massachusetts

Lewis Teperman, MD, FACS
Vice Chair, Organ Transplant Surgery
Director, Organ Transplantation
Professor of Surgery and Medicine
Zucker School of Medicine at Hofstra
Northwell Health
New York, New York

Program Description

As the COVID-19 pandemic continues to devastate the world, it is important for clinicians to recognize the most vulnerable populations, such as immunocompromised people. They are unlikely to mount a full response to COVID-19 vaccinations and have a higher risk of both severe outcomes if infected and easier transmission to uninfected people. An Emergency Use Authorization (EUA) was recently granted for pre-exposure prophylaxis in immunocompromised people, and it is critical that clinicians are aware of data, EUA criteria, and patient prioritization strategies. Dr. Jonathan Li and Dr. Lewis Teperman discuss EUA criteria, which conditions place patients most at risk for COVID-19, vaccination response in immunocompromised patients, and patient stratification.

Target Audience

The educational design of this activity addresses the needs of oncology, organ transplantation, nephrology, infectious disease, and other clinicians with a significant focus on managing immunocompromised patients.

Learning Objectives

After completing this activity, participants will be better prepared to:

  • Identify candidates for preexposure prophylaxis with anti-SARS-CoV-2 monoclonal antibodies, including immunocompromised patients

Physician Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group and Integritas Communications. Global Education Group is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation

Global Education Group designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Continuing Education

This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners (AANP) through the joint providership of Global Education Group and Integritas Communications. Global Education Group is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 0.25 contact hour(s) (which includes 0.1 hour(s) of pharmacology).

Disclosure of Conflicts of Interest

Global Education Group adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the ACCME and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.

All relevant financial relationships have been mitigated.

The faculty have the following relevant financial relationships with ineligible companies:

Jonathan Li, MD - Consulting Fee: AbbVie Inc.

Lewis Teperman,MD - Nothing to disclose

The planners and managers have the following relevant financial relationships with ineligible companies:

Kristin Delisi, NP: Nothing to disclose
Lindsay Borvansky: Nothing to disclose
Andrea Funk: Nothing to disclose
Liddy Knight: Nothing to disclose
Ashley Cann: Nothing to disclose
Gena Dolson, MS: Nothing to disclose
Rose O’Connor, PhD, CHCP: Nothing to disclose

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group and Integritas Communications do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Instructions to Receive Credit

In order to received credit, participants must complete the following:

  1. Read the educational objectives, accreditation information, and faculty disclosures at the beginning of this activity.
  2. Complete the Preactivity Questions.
  3. Review the activity content.
  4. Achieve a grade of 70% on the Postactivity Test Questions and complete the Evaluation.

Term of Offering

This activity was released on April 1, 2022, and is valid for one year. Requests for credit must be made no later than April 1, 2023. 

Fee Information & Refund/Cancellation Policy

There is no fee for this educational activity.

Global Education Group Contact Information

For information about the accreditation of this program, please contact Global Education Group at 303-395-1782 or

Click "Begin Activity" to acknowledge that you have reviewed the preamble information for this activity.

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credit amount 0.25

credit type CME/AANP

release 04/01/2022

expiration 04/01/2023

type POC101