Real-World Use of Anti-SARS-CoV-2 Monoclonal Antibodies Module 2

Monica Gandhi, MD, MPH; Lucy Horton, MD, MPH

This activity is jointly provided by Global Education Group and Integritas.


This educational activity is supported by an educational grant from GlaxoSmithKline.

Target Audience

The educational design of this activity addresses the needs of infectious disease clinicians, internal medicine clinicians, and primary care providers, including physicians, nurse practitioners, and physician assistants, involved in the care of patients with mild or moderate coronavirus disease 2019 (COVID-19) who are at risk for clinical progression (eg, older patients, immunocompromised patients, patients with certain comorbidities).

Statement of Need/Program Overview

Real-world use of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibodies (mAbs) can be challenging due to constantly changing guidelines, barriers to care, and a limited window to treat patients diagnosed with COVID-19. Clinic models for identifying patients eligible for treatment and subsequently linking patients to care have been established with great success. Guidelines now include both oral and intravenous antivirals in addition to anti-SARS-CoV-2 mAbs, and clinicians must remain current on available therapies and treatment stratification and prioritization. Drs. Monica Gandhi and Lucy Horton discuss identification of patients with mild to moderate COVID-19, clinic models for linking patients to care, and barriers to care.

Educational Objectives

After completing this activity, the participant should be better able to:

  • Identify patients who qualify for anti-SARS-CoV-2 monoclonal antibody therapy based on current national guidelines
  • Review how to communicate with patients with COVID-19 about the role of anti-SARS-CoV-2 monoclonal antibody therapies to encourage acceptance, decrease the risk of poor outcomes, and reduce disparities


Monica Gandhi, MD, MPH
Professor of Medicine and Associate Chief
Division of HIV, Infectious Diseases, and Global Medicine
University of California, San Francisco (UCSF) School of Medicine
Director, UCSF-Bay Area Center for AIDS Research (CFAR)
Medical Director
“Ward 86” HIV Clinic, San Francisco General Hospital
San Francisco, California

Lucy Horton, MD, MPH
Associate Professor of Medicine
Division of Infectious Diseases and Global Health
University of California San Diego School of Medicine
Medical Director and Infectious Disease Specialist
COVID-19 Employee Health and Contact Tracing Group
Ambulatory COVID Drive Up and Results Team Services
UC San Diego Health
San Diego, California

Physician Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Integritas.  Global is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation

Global designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Continuing Education

This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners (AANP) through the joint providership of Global and Integritas Communications. Global is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 0.25 contact hour(s) (which includes 0.0 hour(s) of pharmacology).

Instructions to Receive Credit

In order to receive credit for this activity, the participant must complete the preactivity questionnaire, score 100% on the posttest, and complete the program evaluation.

Global Contact Information

For information about the approval of this program, please contact Global at 303-395-1782 or

Fee Information & Refund/Cancellation Policy

There is no fee for this educational activity.

Disclosures of Conflicts of Interest

Global adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global.  All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias. 

All relevant financial relationships have been mitigated.

The faculty have the following relevant financial relationships with ineligible companies:

Monica Gandhi, MD, MPH: Nothing to disclose

Lucy Horton, MD, MPH: Consulting Fee: Gilead Sciences, Inc., GlaxoSmithKline

The following planners and managers have no relevant financial relationships with ineligible companies:

Kristin Delisi, NP, Lindsay Borvansky, Andrea Funk, Liddy Knight, Ashley Cann, Gena Dolson, MS, Rose O'Connor, PhD, CHCP, Jim Kappler, PhD

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration. Global and Integritas Communications do not recommend the use of any agent outside of the labeled indications. 

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

System Requirements

1.4 GHz Intel Pentium 4 or faster processor (or equivalent)
Windows 10, 8.1 (32-bit/64-bit), Windows 7 (32-bit/64-bit)
512 MB of RAM (1 GB recommended)
Microsoft Internet Explorer 11 or later, Windows Edge browser, Mozilla Firefox, and Google Chrome
For HTML Client – Google Chrome (v70.0 & above), Mozilla Firefox (v65.0 & above), and Edge (v42.0 & above)

1.83 GHz Intel Core Duo or faster processor
512 MB of RAM (1 GB recommended)
MAC OS X 10.12, 10.13 and 10.14
Mozilla Firefox, Apple Safari, Google Chrome
For HTML Client – Google Chrome (v70.0 & above), Apple Safari (v12.0 & above), and Mozilla Firefox (v65.0 & above)

Click "Begin Activity" to acknowledge that you have reviewed the preamble information for this activity.

Begin Activity

credit amount 0.25

credit type CME/CE

release 06/07/2022

expiration 06/07/2023

type POC101