Mylynda B. Massart, MD, PhD
Associate Professor
Director, University of Pittsburgh Medical Center (UPMC) Primary Care Precision Medicine Center
Co-Director, HUB Core: Integrating Special Populations and Community Partners Core
Clinical and Translational Science Institute (CTSI)
Institute for Precision Medicine
University of Pittsburgh
Pittsburgh, Pennsylvania

Target Audience 

The educational design of this activity addresses the needs of primary care physicians (PCPs), internists, obstetricians, geriatricians, and public health clinicians. 

Program Overview 

In this “Top 10 Early Cancer Detection Queries” program, Dr. Mylynda Massart answers the 10 questions most commonly asked by primary care clinicians about blood-based multi-cancer early detection (MCED) tests. Some of the topics addressed are the science behind MCEDs, their accuracy, how MCEDs compare to other screening modalities, and integration of MCED testing into primary care practice. 

Educational Objectives  

After completing this activity, participants should be better able to: 

  • Explain how blood-based biopsy has the potential to fill current screening gaps and limitations through the use of cell-free DNA analysis for multi-cancer early detection (MCED)  
  • Assess the accuracy, advantages, disadvantages, cost-effectiveness, and utility of available and emerging MCED tests as demonstrated by current and evolving clinical data  
  • Describe practical protocols for integrating MCED and patient counseling in the primary care setting.

Physician Accreditation Statement 

Global Education Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.  

Physician Credit Designation 

Global Education Group designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Nurse Practitioner Continuing Education 

This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners (AANP) through the joint providership of Global Education Group and Integritas Communications. Global Education Group is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 0.50 contact hour (which includes 0.0 hours of pharmacology). 

Global Contact Information 

For information about the approval of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com

Instructions to Receive Credit 

To receive credit for this activity, participants must complete the preactivity questionnaire, complete and receive a minimum score of 70% on the posttest, and complete the program evaluation. 

Fee Information & Refund/Cancellation Policy 

There is no fee for this educational activity. 

Disclosures of Relevant Financial Relationships 

Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.

All relevant financial relationships have been mitigated.  

The faculty have the following relevant financial relationships with ineligible companies: 

Mylynda B. Massart, MD, PhD - Speakers Bureau: GRAIL (cancer screening) 

The planners and managers from Global Education Group and Integritas Communications have no relevant financial relationships with ineligible companies to disclose. 

Disclosure of Unlabeled Use 

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration. Global Education Group (Global) and Integritas Communications do not recommend the use of any agent outside of the labeled indications.   

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. 

Begin Activity
available resources
linked resources
Suggested Reading
Top 10

Top 10 Early Cancer Detection Queries

What You Need to Know About Blood-Based Screening in Primary Care